Appetite, Satiety
Conditions
Brief summary
Participants will be given a drink (and no drink for one of the treatments) prior to a pizza dinner. Ratings on satiety, appetite and desire to eat will be asked with the use of a questionnaire. Blood glucose will also be measured. One hour after the drink, participants will be given a pizza and can eat as much as they want. The pizza remaining will be weighed.
Detailed description
Each participant will receive all three treatments on separate occasions in random order (separated by a week). The three treatments include control (no supplement), carbohydrates - protein (Generation UCAN supplement, 250ml, 10% solution) and carbohydrates alone (Mirexus PhytoSpherix, 250ml, 10% solution). Participants will report to the lab between 4-5 pm and 4 hours after their last meal on day they have not exercised. Participants will record food intake the day of the first experiment and will be asked to replicate both type and quantity for subsequent visits. Upon arrival at the lab, baseline measures (blood glucose as well as rating of satiety ratings, appetite and desire to eat (10-point visual analogue scale). Then the treatment will be given and all the aforementioned variables will be remeasured at 15, 30, 45 and 60 minutes post drink. At 65 minutes, participants will be provided with an ad libitum pizza meal. Participants will be told to eat until they are comfortably full (Bellissimo et al., 2008). The pizza provided will be weighed initially and once the participant is done eating and has left the lab, the remaining pizza will be weighed and recorded. The pizza will be a cheese only pizza to minimize any difference in energy intake due to the location of additional items placed on the pizza. Participants will not be told the true purpose of this experiment, instead they will be told that the pizza meal is a reward for participating in the study. Later, at the conclusion of the study all will be debriefed.
Interventions
DIETARY_SUPPLEMENTGeneration UCAN supplementation
carbohydrates - protein (Generation UCAN supplement, 250ml, 10% solution)
DIETARY_SUPPLEMENTMirexus PhytoSpherix supplementation
carbohydrates alone (Mirexus PhytoSpherix, 250ml, 10% solution)
BEHAVIORALsatiety ratings
questionnaire on satiety ratings will be provided to participants 15, 30, 45 and 60 min after the drink (or no drink)
Sponsors
Western University, Canada
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy males and females at the age of 18-40 * sedentary individuals
Exclusion criteria
* exercise more than twice per week * does not like pizza * do not eat three meals a day * medications that affect eating patterns * have metabolic and gastrointestinal diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| changes in satiety ratings after the drink | 15, 30, 45, 60 min after the drink | satiety ratings will be asked with the use a 10 point visual analog scale (VAS) questionnaire, 10 being do not want to consume any more food and 1 being strong desire to consume food |
| Food intake | 90 min after the drink | food intake after each treatment will be measured by weighing the left over pizza slices |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| changes in appetite ratings after the drink | 15, 30, 45, 60 min after the drink | appetite ratings will be asked with the use a 10 point visual analog scale (VAS), 10 being strong desire to consume food and 1 being no desire to consume food at all |
| changes in blood glucose after the drink | 15, 30, 45, 60 min after the drink | blood glucose will be measured through finger pricks |
| changes in desire to eat ratings | 15, 30, 45, 60 min after the drink | desire to eat ratings will be asked with the use a 10 point visual analog scale (VAS), 10 being no desire to eat at all and 1 being strong desire to eat |
Countries
Canada
Contacts
Primary ContactCrystal Lee, BSc
Backup ContactManuel Quinones, MSc
Outcome results
None listed