Action Observation Treatment in Parkinson's Patients

Action Observation Treatment and Motor Imagery as Rehabilitation Tools in Parkinson's Disease Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04181918

Acronym

AOT-PA

Enrollment

Registered

2019-12-02

Start date

2018-03-26

Completion date

2020-06-26

Last updated

2019-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson

Keywords

Action Observation Treatment, Motor Imagery, Randomized Controlled Study

Brief summary

The aim of the study is to assess the role of Action Observation Treatment (AOT) and Motor Imagery (MI) in the rehabilitation of Parkinson's disease patients, as compared to a control condition. Main outcome measures will be the results in two functional scales (FIM, UPDRS) and kinematics parameters obtained from gait analysis. Data at two months and six months follow up, respectively, will be also collected.

Interventions

BEHAVIORALAOT

During action observation, participants observe different daily actions (e.g. reading a newspaper; drinking an espresso) divided into up to four motor segments.

BEHAVIORALMI

During motor imagery, participants imagine themselves performing the same daily actions as in AOT in the absence of motor output

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Parkinson disease patients on Hoehn and Yahr 3-4

Exclusion criteria

* Mini-Mental State Examination \< 24 * Fluent aphasic patients * Apraxia * Neglect * major neuropsychiatric disorders

Design outcomes

Primary

Measure	Time frame	Description
change in the functional status of the patient	Before treatment, within one week after treatment, two months' follow up	to assess the change in the functional status of the patient, the Functional Independence Measure (FIM) will be used. FIM consists in a 7-point scale (1 = \<25% independence; total assistance required, 7 = 100% independence), and it can detect changes in the patient's status in 18 categories, focusing on motor and cognitive function. Functional patients' status will assess before treatment, within one week after the end of the treatment (after treatment) and two months' follow up.
change in Parkinson disease motor symptoms	Before treatment, within one week after treatment, two months' follow up	to assess the change in motor status of the patient, the Unified Parkinson's Disease Rating Scale (UPDRS) will be used, and it consists in a 5-point scale (0 = no signs; 4 = severe). UPDRS will be administered before treatment, within one week after the end of the treatment (after treatment) and two months' follow up.
change in kinematic parameters of the gait (velocity, footing, pace, step length)	Before treatment, within one week after treatment, two months' follow up	to assess the change of patient's gait parameters, the kinematic analysis will be used (i.e. gait analysis). The gait analysis allows to detect fine-grain changes in kinematic parameters of the movement, through a non-invasive methodology. Gait analysis will be performed before treatment, within one week after the end of the treatment (after treatment) and two months' follow up.

Countries

Italy

Contacts

Primary ContactGiovanni Buccino

neurofis.buccino@gmail.com00390521205683

Backup ContactClaudio Rovacchi

crovacchi@dongnocchi.it00390521205683

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026