Surface Finish
Conditions
Keywords
dental implant, zirconia, biofilm
Brief summary
The aim is to test the influence of surface finish on biofilm formation on the transmucosal part of zirconia implants in an in vivo study. Sixteen test person will therefore receive an orthodontic apparatus containing the specimens with the respective surfaces and carry them for 2x 24h. The primary outcome is the spectormetrical quantification (OD value) of biofilm on the specimens that have been carried by the test person over 24h. Biofilm will be analysed using scanning electron microscopy.
Interventions
OTHERImplant neck surface
The biofilm formation is tested on discs manufactured of zirconia with different surfaces in vivo using orthodontic devices that the participants carry over 24h
Sponsors
University of Basel
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* No systematic antibiotic therapy during the last 3 months * Good oral health and compliance (PI and BI \<20%) * No sign of parodontal disease or other inflammatory changes in the mouth * Non-smoker
Exclusion criteria
* Disease that requires antibiotic therapy * Pressure marks due to the orthodontic apparatus that can not be eliminated * Other unexpected complications that could be related to the orthodontic apparatus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Safranin Staining | 3 months | The biofilm on the discs is quantified using safranin staining and evaluated with the measurement of optical density using a photospectrometer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| SEM | 3 months | The morphology of the biofilm is analyzed using scanning electron microscopy |
Countries
Switzerland
Outcome results
None listed