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Applying Pulse Wave Analysis to Predict Intradialytic Hypotension

Applying Pulse Wave Analysis to Predict Intradialytic Hypotension

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04180514
Enrollment
70
Registered
2019-11-27
Start date
2014-09-01
Completion date
2016-12-17
Last updated
2019-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intradialytic Hypotension

Keywords

intradialytic hypotension, pulse wave analysis, heart rate variability, Constitution in Chinese Medicine Questionnaire

Brief summary

Intradialytic hypotension (IDH) is a common complication during hemodialysis in patients with chronic kidney disease and may increase the mortality. This study aimed to investigate whether pulse wave analysis could be the predictor of IDH. In this study, patients under regular hemodialysis were enrolled from Taoyuan Chang Gung memorial hospital. Subjects were evaluated by pulse wave instrument, heart rate variability analyzer and Constitution in Chinese Medicine Questionnaire before hemodialysis. According to the definitions of IDH, subjects in study group and control group were confirmed by the dialysis records. Furthermore, repeated examinations were done for 3 hemodialysis to investigate the possible predictive factors for IDH.

Detailed description

Intradialytic hypotension (IDH) is a common complication during hemodialysis in patients with chronic kidney disease and may increase the mortality. This study aimed to investigate whether pulse wave analysis could be the predictor of IDH. In this study, patients under regular hemodialysis were enrolled from Taoyuan Chang Gung memorial hospital. Subjects were evaluated by pulse wave instrument, heart rate variability analyzer and Constitution in Chinese Medicine Questionnaire before hemodialysis. According to the definitions of IDH, subjects in study group and control group were confirmed by the dialysis records. Furthermore, repeated examinations were done for 3 hemodialysis to investigate the possible predictive factors for IDH.

Interventions

DIAGNOSTIC_TESTintradialytic hypotension episode

Intradialytic hypotension episode under regular hemodialysis

Sponsors

Chang Gung Memorial Hospital
CollaboratorOTHER
Taipei Veterans General Hospital, Taiwan
CollaboratorOTHER_GOV
China Medical University, Taiwan
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients under regular hemodialysis (3 times per week) in last 3 months

Exclusion criteria

* arrhythmia * artery-vein anastomoses on both arms * other conditions which might interfere the evaluation of pulse wave analysis and heart rate variability analysis

Design outcomes

Primary

MeasureTime frameDescription
Pulse wave analysiswithin 2 hours before regular dialysisPulse wave analysis
Heart rate variabilitywithin 2 hours before regular dialysisHeart rate variability
Constitution in Chinese Medicine Questionnairewithin 2 hours before regular dialysisConstitution in Chinese Medicine Questionnaire

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026