Anal Fistula
Conditions
Brief summary
Anal Fistula can be a challenging condition to treat. Microdialysis has never before been used to examine the inner environment of anal fistula. This is now going to be performed.
Detailed description
Patients with anal fistula can have a reduced quality of life for years do to fistula complications. This condition is not well researched and more knowledge is needed to provide better care. Microdialysis has been used to study other organs of the body such as the brain, liver and GI-tract. Upcoming study is going to study the inner environment of the anal fistula in regards to lactate, pyruvate and glucose. The study group is patients with anal fistula that with a need for seton treatment. Measurements with microdialysis will take place before operative procedure and one month after getting their seton inserted.
Interventions
DEVICEOnZurf Probe, Senzime AB, Uppsala, Sweden
Probe is inserted into the fistula and measurements are made of the inner environment.
Sponsors
University Hospital, Umeå
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Microdialysis is used to investigate the inner enviorment of anal fistulas. The patient will be its own control with measurements at prior to intervention and after operative procedure.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* over 18 years of age * to be able to understand and accept the terms of study
Exclusion criteria
* age under 18 * dementia, language barrier
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurements of glucose in anal fistula using microdialysis | baseline measurement, 1 month follow up | measurements of glucose in fistula using microdialysis, change in value is being assessed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measurement of pyruvate in anal fistula using microdialysis | baseline measurement, 1 month follow up | measurement of pyruvate measurements in fistula using microdialysis, change in value is being assessed |
Other
| Measure | Time frame | Description |
|---|---|---|
| measurement of lactate in anal fistula using microdialysis | baseline measurement, 1 month follow up | measurement of lactate in fistula using microdialysis, change in value is being assessed |
Countries
Sweden
Contacts
Primary ContactKarin Strigard, Associate Professor
Backup ContactKarin Adamo, PhD student
Outcome results
None listed