Postprandial Hyperglycemia
Conditions
Keywords
older people, nutrition, dairy, berries, postprandial, glucose, insulin
Brief summary
Malnutrition or its risk is common among older people. To maintain adequate nutrition, increased meal frequency is important. In addition to main meals, regular consumption of nutrient- and energy-dense snacks is recommended. The study examines the post-meal responses to dairy- and berry-based snacks tailored for older people. The plasma concentrations of glucose, insulin and free fatty acids are measured during three hours after snack consumption. In addition, subjective satiety responses and heart rate variability are recorded.
Interventions
DIETARY_SUPPLEMENTDairy snack
The effects of dairy snack are compared with orange juice.
DIETARY_SUPPLEMENTBerry snack
The effects of two berry snacks are compared with berry soup.
Sponsors
University of Eastern Finland
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Home-dwelling
Exclusion criteria
* Smoking * Type 1 diabetes * Type 2 diabetes treated with oral medications or insulin * Cognitive impairment * Antibiotic medication within the past 3 months * Blood donation within the past month
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in postprandial glucose | 3 hrs | Changes in plasma glucose concentration within 3 hrs after meal |
| Change in postprandial insulin | 3 hrs | Changes in plasma insulin concentration within 3 hrs after meal |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in postprandial free fatty acids | 3 hrs | Changes in plasma free fatty acid concentration within 3 hrs after meal |
| Change in postprandial satiety scores assessed by using visual analogy scales | 3 hrs | Visual analogue scales (VAS) are used to assess satiety and other related subjective sensations (fullness, hunger, desire to eat, alertness) within 3 hrs after meal. Each VAS consists of a 100-mm horizontal line anchored with verbal descriptions at each end expressing the weakest (0 mm) or strongest (100 mm) statement of sensation. Results are scores between 0 and 100. |
| Heart rate variability | 3 hrs | Electrocardiography monitoring for assessment of several variables of heart rate variability |
Countries
Finland
Outcome results
None listed