Obesity, Childhood
Conditions
Brief summary
Using retrospective data from the Vanderbilt University Medical Center electronic health record, the investigators will study the association between mother's weight / weight change before and during pregnancy and the development of childhood obesity up until 5 years of age.
Detailed description
The investigators are extracting de-identified retrospective data from the Vanderbilt University Medical Center electronic health record for mother-child pairs. From this data, the investigators will study the association between mother weight change during pregnancy and the risk of her child developing obesity during the first 5 years of life. Included mothers must have at least one weight measurement and at least one height measurement; they must have at least one child with weight/length measurements at birth and one additional same day height/weight measurement at or before 5 years of age.
Interventions
None listed
Sponsors
Patient-Centered Outcomes Research Institute
University of Pennsylvania
Vanderbilt University Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Mother-child pairs in the Vanderbilt University Medical Center (VUMC) electronic health record. * The mothers must have at least one height measurement. * The mothers must also have at least one weight measurement during pregnancy. * The child must have birth length and weight measures and at least one same day height/weight measurement during their first 5 years of life.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life | first 5 years of child's life | Obesity of the child is defined as having a BMI-by-age classification greater than the 95th percentile based on the US CDC percentiles. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Mother-Child Mothers who have delivered at VUMC and their children who are seen by Vanderbilt-affiliated physicians. | 20,670 |
| Total | 20,670 |
Baseline characteristics
| Characteristic | Mother-Child |
|---|---|
| Age, Continuous Child Age at delivery | 0 years |
| Age, Continuous Maternal Age at delivery | 28 years |
| Ethnicity (NIH/OMB) Hispanic or Latino | 3082 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 17168 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 420 Participants |
| Race (NIH/OMB) American Indian or Alaska Native | 154 Participants |
| Race (NIH/OMB) Asian | 1420 Participants |
| Race (NIH/OMB) Black or African American | 4778 Participants |
| Race (NIH/OMB) More than one race | 82 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 1458 Participants |
| Race (NIH/OMB) White | 12778 Participants |
| Region of Enrollment United States | 20670 participants |
| Sex: Female, Male Child sex Female | 4887 Participants |
| Sex: Female, Male Child sex Male | 5448 Participants |
| Sex: Female, Male Maternal sex Female | 10335 Participants |
| Sex: Female, Male Maternal sex Male | 0 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 0 |
| other Total, other adverse events | 0 / 0 |
| serious Total, serious adverse events | 0 / 0 |
Outcome results
Primary
Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life
Obesity of the child is defined as having a BMI-by-age classification greater than the 95th percentile based on the US CDC percentiles.
Time frame: first 5 years of child's life
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Mother-Child | Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life | 1845 Participants |