Bariatric Surgery Candidate, Obesity
Conditions
Brief summary
This research will study the bone fragility in obese patients, on DXA and CT-scan, in a transversal study. The investigators want also to study the specific risk factors of bone fragility in these obese patients (relationship between body composition on whole body on DXA, fat mass and its location, lean mass, weight loss after surgery and SBAC-L1), to improve the bone screening.
Interventions
DIAGNOSTIC_TESTDXA and CT-scan
DXA and CT-scan are usually performed during the following of these patients before bariatric surgery
Sponsors
Centre Hospitalier de Toul Saint Charles
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients followed at Nancy university hospital for a bariatric surgery * CT-scan and DXA performed before surgery, with maximum 1 year before the 2 exams
Exclusion criteria
* \< 18 years * Protected adults
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| scanographic bone attenuation coefficient of the first lumbar vertebra SBAC-L1 | November 2019-September 2020 | on axial section of the first lumbar vertebra, with a region of interest |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Vertebral fracture | November 2019-September 2020 | According Genant classification, on sagittal section of spine |
| DXA: T-score | November 2019-September 2020 | in standard deviation, on spine / hip / femoral neck / wrist |
| DXA: Bone mineral density BMD (spine, hip , femoral neck, wrist) | November 2019-September 2020 | in g/cm² |
| DXA: lean and fat mass | November 2019-September 2020 | in % and repartition of each |
Countries
France
Outcome results
None listed