Delirium, Neurocognitive Disorders
Conditions
Brief summary
To assess self-reported cognitive function and health-related quality of life in patients with and without early postoperative delirium
Detailed description
Neurocognitive disorders including postoperative delirium are a serious complication after surgery and anesthesia in the elderly. Postoperative delirium is an acute-onset diffuse brain dysfunction that is characterized by a fluctuating course of confusion, disorganized thinking, inattention, irritability, disturbances of the circadian rhythm, and disorders of consciousness. Post-anesthesia care unit (PACU) delirium occurs immediately after emergence from anesthesia and affects up to 45% of patients after elective surgery. It is unclear, whether PACU delirium is associated with intermediated or long-term adverse outcomes including neurocognitive disorders or mortality. The aim of this prospective observational was to assess self-reported cognitive function and health-related quality of life in patients with and without PACU delirium three months after radical prostatectomy.
Interventions
None listed
Sponsors
Universitätsklinikum Hamburg-Eppendorf
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* elective radical prostatectomy * \>60 years * fluent in German
Exclusion criteria
* preexisting cognitive impairment * cerebrovascular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Self-reported cognitive failures | three months | Cognitive Failures Questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Health-related quality of life | three months | Short Form Health Survey 36 |
Countries
Germany
Outcome results
None listed