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Biomarkers in Patients Hospitalized With Suspected Acute Myocardial Infarction

Biomarkers in Patients Hospitalized With Suspected Acute Myocardial Infarction

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04167904
Acronym
BIOMAC
Enrollment
4446
Registered
2019-11-19
Start date
2019-12-10
Completion date
2023-04-01
Last updated
2025-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction, Acute

Keywords

Troponin I, Myocardial Infarction, Sensitivity and Specificity, Receiver operation characteristics curve, Biomarkers

Brief summary

The concentration of troponins in plasma is used for diagnosing acute myocardial infarction. Different types of heart-specific troponins can be measured and with different analytical methods. The primary aim of this study is to evaluate the diagnostic characteristics of a new analytical method for measuring troponin I in diagnosing acute myocardial infarction.

Interventions

None listed

Sponsors

Norwegian University of Science and Technology
CollaboratorOTHER
St. Olavs Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* hospitalized at St. Olavs hospital * blood sampled for troponin analysis due to suspicion of acute myocardial infarction without ST-elevations on ECG less than 4 hours after admitted to the hospital

Exclusion criteria

* residency outside Norway * does not understand Norwegian

Design outcomes

Primary

MeasureTime frameDescription
Acute myocardial infarction according to the 4th universal definition of myocardial infarctionBefore discharge from hospital, a median of 2 daysMetric: Yes/No

Secondary

MeasureTime frameDescription
Days between hospital discharge and deathWithin 30 days after hospital dischargeMetric: Days. The secondary outcome measures will be combined into a composite endpoint reflecting the time between hospital admission and the first secondary outcome measure
Days between hospital discharge and acute myocardial infarction according to the 4th universal definition of myocardial infarctionWithin 30 days after hospital dischargeMetric: Days.
Days between hospital discharge and coronary revascularizationWithin 30 days after hospital dischargeMetric: Days

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026