Women's Health
Conditions
Keywords
Estrogen, Progesterone, Menstrual Cycle, Resistance Training
Brief summary
Although there are numerous studies showing effects of aerobic training on sex hormone concentrations, research analyzing the fluctuation of sex hormones in response to resistance training (RT) is lacking. The objective of this project is to analyze estradiol (E2) and progesterone (P4) responses to an acute resistance training session throughout different phases of the menstrual cycle. This proposed research has strong implications for exercise prescription and for women in general, but more importantly will allow exercise physiologists, coaches, personal trainers, or nutritionists optimize exercise programming around women's menstrual cycle.
Interventions
BEHAVIORALResistance Training
Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest
Sponsors
Southern Illinois University Edwardsville
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Participants will be blocked (four participants by block) and then randomized to start in one of the four menstrual cycle phases (EFP, LFP, ELP, or LLP). Their will be complete once they have gone through the four phases.
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Eumenorrheic females * Age 18-45 years old * BMI of 18.5-34.99 kg/m2
Exclusion criteria
* Practice exercise more than 2 days/week in the last 3 months. * Cardiovascular, metabolic, pulmonary or muscular-skeletal condition * Taking medications that affect metabolism (e.g. oral contraceptives) * Irregular menstrual cycles
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in estrogen concentrations | through study completion, an average of 5 weeks | Estrogen concentrations will be obtained from blood samples assessed using through ELISA kits |
| Change in progesterone concentrations | through study completion, an average of 5 weeks | Progesterone concentrations will be obtained from blood samples assessed using through ELISA kits |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Relative body fat (%) | At baseline: 1 assessment point | Relative body fat (%) will be assessed through Dual-energy X-ray Absorptiometry |
| Skeletal muscle mass (kg) | At baseline: 1 assessment point | Skeletal muscle mass (kg) will be estimated using Dual-energy X-ray Absorptiometry values |
| Cardiorespiratory Fitness | At baseline: 1 assessment point | Cardiorespiratory Fitness will be assessed with a cardiopulmonary exercise test using the Bruce protocol |
| Lean body mass (kg) | At baseline: 1 assessment point | Lean body mass (kg) will be assessed through Dual-energy X-ray Absorptiometry |
| Strength in Leg Press | At baseline: 1 assessment point | Maximal strength in leg press will be assessed using one repetition maximum test |
| Changes in diet | through study completion, an average of 5 weeks | Diet will be assessed using the a 24h dietary recall |
| Strength in Bench Press | At baseline: 1 assessment point | Maximal strength bench press will be assessed using one repetition maximum test |
| Fat mass (kg) | At baseline: 1 assessment point | Fat mass (kg) will be assessed through Dual-energy X-ray Absorptiometry |
Countries
United States
Contacts
Primary ContactMaria Fernandez del Valle, PhD
Outcome results
None listed