Postoperative Pain, Analgesia
Conditions
Brief summary
Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions. Dexketoprofen is a new NSAID treating acute postoperative pain. The purpose of this study is to evaluate the analgesic effect when it is given intravenously or as part of the local infiltration analgesia in patients under spinal anesthesia undergoing unilateral total knee arthroplasty.
Interventions
intravenous dexketoprofen 50mg or intrathecal
Local Infiltration Analgesia
Sponsors
KAT General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* unilateral total knee arthroplasty * accept to enter the study * ASA score I or II * hospitalization for at least 2 days
Exclusion criteria
* allergy in any given medications * active gastrointestinal bleeding or other active bleeding * history of peptic ulcer * renal failure * hepatic failure * chronic heart failure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS Score in 8hours after surgery | 8h | The visual analogue scale or visual analog scale (VAS) is a psychometric response scale which can be used in questionnaires. It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points. 10 describes the worst pain that a person ever imagined. |
| VAS Score 24hours after surgery | 24h | The visual analogue scale or visual analog scale (VAS) is a psychometric response scale which can be used in questionnaires. It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points. |
| VAS Score 48hours after surgery | 48h | The visual analogue scale or visual analog scale (VAS) is a psychometric response scale which can be used in questionnaires. It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points. |
| Total tramadol consumption the first 24hours | 24h | — |
Countries
Greece
Contacts
Primary ContactElena Nikolakopoulou
Outcome results
None listed