Renal Stone
Conditions
Brief summary
The investigators aim to investigate the effect of peritubal local anesthetic infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy.
Detailed description
The investigators aim to investigate the effect of peritubal local anesthetic on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy. Patients aged between 18 and 65 years with renal stone \>2 cm will be included in this study .The patients will be divided into two groups. In Group A , the drug will be infiltrated to the renal capsule, perinephric fat, muscles, subcutaneous tissue, and skin under fluoroscopy with 0.25 percent bupivacaine. This is a widely-used procedure by surgeons in the world. In Group B, no anesthetic will be infiltrated after the end of the procedure.
Interventions
Following PCNL under general anesthesia, patients will receive 0.25% Bupivacaine ( Marcaine) local anesthetic infiltration
Sponsors
Saddam Al Demour
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* 18-70 years of age * body mass index \<35, * renal stone size \>2.0 cm.
Exclusion criteria
* patients having supra-costal puncture. * excessive intraoperative bleeding. * renal stones requiring more than a single puncture. * surgical procedure extending more than 3 hours. * urinary tract infection. * severe cardiopulmonary disease. * abnormal renal function tests. * allergy to local anesthetics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visual analogue scale (VAS ) | 1, 4, 8, 12, 24, and 48 hours | Visual Analogue Scale (VAS), the patient is asked to describe the level of pain on a visual scale at rest at 1, 4, 8, 12, 24, and 48 hours |
| Dynamic Visual Analogue Scale (DVAS) | 1 hour, 4 hours, 8 hours, 12 hours, 24 hours, and 48 hours | Dynamic Visual Analogue Scale (DVAS), the patient is asked to describe the level of pain on a visual scale during breathing at 1, 4, 8, 12, 24, and 48 hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The time for the first opioid demand | 48 hours | first post op time for analgesia |
| the number of opioid demands | 48 hours | total number of opioid given to the patient |
| total opioid consumption | 48 hours | total amount of opioid consumption |
Countries
Jordan
Outcome results
None listed