Pulmonary Segmentectomy
Conditions
Brief summary
Recently developed fluorescence-navigated thoracoscopy with indocyanine green (ICG) is being used for various kinds of pulmonary surgery, and several studies have reported the application of this novel technique in demarcation of the intersegmental border for segmentectomy. This study is performed prospectively to find out, for the first time, the optimal dosage of ICG in human body to ensure safe and sustained imaging during segmentectomy.
Interventions
PROCEDUREIndocyanine Green Injection through Peripheral Vein
After ligation of the segmental pulmonary artery supplying the targeted segment, indocyanine is injected intravenously at a specific concentration intraoperatively.
Sponsors
Beijing Municipal Science & Technology Commission
Peking University People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Suitable for segmentectomy and signed informed consent
Exclusion criteria
* Liver dysfunction. * Allergic to indocyanine green. * Can't tolerate thoracoscopic surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Signal-to-background Ratio (SBR) of the Targeted and Non-targeted Segments | Surgery | We use image analysis software ImageJ to evaluate the strength of luminosity in the targeted and non-target segments using intraoperative images and calculate signal-to-background-ratio. |
Countries
China
Contacts
Primary ContactFeng Yang, MD
Backup ContactTiezheng Li, MD
Outcome results
None listed