Respiratory Complication
Conditions
Brief summary
Intra hospital transport of ICU patients is still at high risk of respiratory complications.We propose to determine if endotracheal tube clamping prior to disconnect ventilator allows to avoid oxygenation decrease.
Detailed description
Changing respiratory support and multiples endotracheal tube disconnections may induce a loss of PEEP and finally lead to alveolar derecruitment. This study is an evaluation of a care procedure to limit the incidence of alveolar derecruitment in ventilated intubated ICU patients during transport for CT scan. Intra hospital transport of ICU patients are performed by anesthesiologist nurses, the physician entrusts them this activity. This is a randomized controlled study, the procedure is to clamp endotracheal tube before each disconnection from ventilator.
Interventions
PROCEDUREClamping of the ventilator endotracheal tube
The transport will be released in accordance with SFAR SRLF guideline. Before each disconnection from ventilator endotracheal tube will be clamped.
Sponsors
University Hospital, Montpellier
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* intensive care patient * intubated, sedated, controlled assisted ventilation * Intra hospital transport for CT scan * arterial catheter * the patient or his trusted person consent to the study
Exclusion criteria
* Patient Covid tests positive or Covid test results not received * extubated, unsedated, * reinforced tube * tracheotomy * pregnancy * guardianship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measure of the pa02/Fi02 | 1 hour after the end of the transport | Evaluate the effectiveness of a procedure to avoid alveolar delisting, measured by the absence of a decrease in the PaO2/FiO2 ratio (before transport and 1 hour after return to bed) during an HIT performed by a nurse anaesthetist/caregiver team, of intubated and ventilated resuscitation patients in a controlled assisted volume. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of the pa02 | 1 hour after the end of the HIT | Evaluate the impact of the procedure on the absence of PaO2 reduction (before transport and 1 hour after return to bed) |
| length of stay | up to 28 days | Evaluate the impact of the intervention on the length of ICU stay |
| duration of invasive ventilation | up to 28 days | Evaluate the impact of the intervention on the invasive ventilation |
| occurrence of adverse events during the HIT | immediately after the end of the HIT | occurrence of adverse events related to the clamping |
Countries
France
Outcome results
None listed