Hip Dysplasia
Conditions
Brief summary
Explore the influence of hip replacement on lower extremity hemodynamics in Crowe Ⅳ hip dysplasia patient.
Detailed description
Changes of limb length after total hip replacement is common, especially for Crowe Ⅳ hip dysplasia patient. Such change potentially increases tension of vessel and influence lower extremity hemodynamics. Till now, little is known in this area.
Interventions
PROCEDUREtotal hip replacement with subtrochanteral osteotomy
applying subtrochanteral osteotomy during the operation to release the tension of vessels and nerve
PROCEDUREtotal hip replacement with no osteotomy
just total hip replacement
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Unilateral Crow IV hip dysplasia; * Bilateral Crow IV hip dysplasia without osteoarthritis on the other side
Exclusion criteria
* Patients with serious medical disease; * Patients with lower extremity vascular disease; 3. Patients with severe mental illness.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hip Harris Score | preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. | change of hip harris score scale from baseline(preoperative) to 1 year after surgery. |
| Leg Length Change | preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. | change of Leg Length from baseline(preoperative) to 1 year after surgery. |
| Radiographic Results | 1 week, 12 weeks, 24 weeks and 1 year after the surgery. | change of Radiographic Results from 1 week after surger to 1 year after surgery |
| Lower Limb Arterial CT Angiography | preoperative, 1 week, 12 weeks after the surgery. | change of vascular diameter and vascular cross-sectional from baseline(preoperative) to 1 year after surgery baseline(preoperative) to 12 weeks after surgery. |
| Vascular Ultrasound Examination | preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. | change of systolic peak velocity, end-diastolic velocity, pulsation index, resistance index and blood flow from baseline(preoperative) to 1 year after surgery. |
| Blood Viscosity | preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. | change of blood viscosity from baseline(preoperative) to 1 year after surgery. |
Contacts
Primary ContactSHIGUI YAN, MD
Outcome results
None listed