Sepsis, Surgery--Complications, Urolithiasis
Conditions
Brief summary
Sepsis is a lethal complication of flexible ureteroscopy. The aim of this study is to identify predictors of sepsis after flexible ureteroscopy in patients with solitary proximal ureteral stones.
Interventions
PROCEDUREflexible ureteroscopy
flexible ureteroscopy is used to removed the stone. If a double-J stent was inserted pre-operatively, it was removed at the beginning of surgery. Rigid ureteroscopy was routinely used for ureteral dilatation before fURS. A 0.035 mm guidewire was advanced through the urethral and ureteral meatuses to the renal pelvis under direct rigid ureteroscope vision. A 14-Fr ureteral access sheath (Cook Medical, Bloomington, IN) was then passed over the wire to the ureteropelvic junction, and 7.5-Fr fURS (Flex-X2, Karl Storz, Germany) was performed through the sheath. Intrarenal pressure was stabilized by a pressure-sensitive pump (Shenda Medical, China). Holmium: yttrium-aluminum-garnet laser was used to fragment the stones. After lithotripsy, 6-Fr double-J stent was routinely inserted in all cases for 2-4 weeks.
Sponsors
Tongji Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* history of fURS to treat unilateral, solitary, and proximal ureteral stones * age ≥18 years
Exclusion criteria
* anatomical renal abnormalities such as transplant kidney, solitary kidney, horseshoe kidney, and kidney duplication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complication-sepsis | within 48 hour after surgery | sepsis is defined as the concurrence of infection and at least 2 of the following 4 criteria: (1) body temperature \>38°C, (2) heart rate \>90/minute, (3) respiratory rate \>20/minute, and (4) leukocyte count \<4,000 cells/μL or \>12,000 cells/μL |
Countries
China
Outcome results
None listed