COPD
Conditions
Brief summary
The aim of this study is to investigate the use helmet ventilation (HV) in walking test and analysis of effect patients with COPD.
Detailed description
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation with chronic inflammation of the respiratory system. Symptoms of COPD may contribute to activity restriction, deconditioning and exercise intolerance. Non-invasive positive pressure ventilation (NIPPV) has been shown to improve exercise intolerance and health-related quality of life in patients with severe COPD. Helmet ventilation (HV) is a new option for NIPPV to alternative to nasal or face mask. A study which published on JAMA demonstrated the feasibility and benefits of HV. The aim of this study is to investigate the use helmet ventilation (HV) in walking test and analysis of effect patients with COPD.
Interventions
DEVICEHelmet vetilation
We will apply non-invasive positive pressure ventilation via a helmet as interface
Sponsors
Fu Jen Catholic University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patents with COPD who confirm by pulmonary function test
Exclusion criteria
* COPD AE within 3 months * Diagnosed neuromuscular disease * Unable to perform 6-MWT
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 6WMD | 2 days | Walking distance of six minute walking test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | 2 days | Heart rate of six minute walking test |
| Respiratory rate | 2 days | Respiratory rate of six minute walking test |
| modified Borg dyspnea scale | 2 days | A self report level of dyspnea score ranging from 0 to 10, 0 represent no dyspnea and 10 represents the worse |
Countries
Taiwan
Outcome results
None listed