Aging Well, Vitamin D Deficiency
Conditions
Keywords
Vitamin D, Bioavailability, Aging, Fortified foods, Vitamin D status, 25-hydroxyvitamin D
Brief summary
This randomized controlled trial (RCT) will compare the change in vitamin D status (25-hydroxyvitamin D nmol/L) after a 4 week intervention with 4 groups: 1. Vitamin D enriched (20ug) olive oil emulsion drink 2. Vitamin D enriched (20ug) coconut oil emulsion drink 3. Placebo emulsion drink 4. Vitamin D supplement (20ug) Participants will be randomized to 1 of 4 intervention group. Hypothesis 1: 25-hydroxyvitamin D concentrations are higher in the olive oil emulsion drink group compared to the placebo emulsion drink group post intervention. Hypothesis 2: 25-hydroxyvitamin D concentrations are higher in the olive oil emulsion drink group compared to the coconut oil emulsion drink group post intervention.
Interventions
DIETARY_SUPPLEMENTVitamin D enriched (20 mcg/day) olive oil emulsion drink
Vitamin D enriched (20 mcg/day) olive oil emulsion drink. 30 mL drink daily
DIETARY_SUPPLEMENTVitamin D enriched (20 mcg/day) coconut oil emulsion drink
Vitamin D enriched (20 mcg/day) coconut oil emulsion drink 30 mL drink daily
DIETARY_SUPPLEMENTPlacebo coconut oil emulsion drink
Placebo coconut oil emulsion drink 30 mL drink daily
DIETARY_SUPPLEMENTVitamin D supplement (20 mcg/day)
Vitamin D supplement (20 mcg/day) Pill consumed daily
Sponsors
Department of Agriculture Food and the Marine
University College Dublin
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Masking description
Double Blind
Intervention model description
Parallel Randomized Controlled Trial
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
• Healthy adults
Exclusion criteria
* Pregnant/lactating * Smokers * Individuals who are not free-living * An inability to read, write or understand English * Following a strict diet for any reason, insulin dependent diabetes, coeliac etc. * Disease that requires chronic therapeutic nutritional or medical treatment * Those with conditions that may affect kidney function * Those with osteoporosis * Those taking supplemental vitamin D * Those who have been on a sun holiday in the last 2 months * Those with a milk protein allergy or lactose intolerance
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vitamin D status | Baseline to 28 days | Change in vitamin D status measured as serum 25-hydroxyvitamin D (nmol/L) |
Countries
Ireland
Outcome results
None listed