Thirdhand Smoke Contamination in a Neonatal Intensive Care Unit (NICU)

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04155697

Enrollment

Registered

2019-11-07

Start date

2017-06-07

Completion date

2018-09-11

Last updated

2022-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nicotine Exposure

Brief summary

The purpose of the study is to quantify the efficacy of hand washing (HW) and ethyl alcohol-based hand sanitizer (S) for third-hand smoke (THS) removal in a sub-sample of non-staff smokers using nicotine wipes on adjacent fingers before and after HW/S. The hypotheses are that detectable levels of surface nicotine will remain on participants' fingers, regardless of hand washing (HW) and ethyl alcohol-based hand sanitizer (S) attempts and that greater finger levels of surface nicotine will remain after alcohol sanitization compared to hand washing.

Interventions

DRUG2% Chlorohexidine Gluconate soap

Participants will wash hands for 30 seconds with 2% Chlorohexidine Gluconate soap.

DRUG62% ethyl alcohol-based hand sanitizer

Participants will apply 62% ethyl alcohol-based hand sanitizer for 30 seconds

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

(): * Any non-staff participants visiting the NICU (including friends and family members of the infants' caregivers) * Consented to and provided a finger wipe * Report being a smoker * Smoking status verified by an exhaled carbon monoxide (CO) level of \>7 parts per million

Exclusion criteria

* Unwilling to comply with research procedures (i.e., finger wipes) * Does not speak English.

Design outcomes

Primary

Measure	Time frame	Description
Nicotine level on finger #1	baseline	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.
Nicotine level on finger #2	5 minutes after hand washing or sanitizing	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.
Nicotine level on finger #3	1 hour after hand washing or sanitizing	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026