Postoperative Delirium
Conditions
Brief summary
This study attempts to validate the Greek version of the CAM Diagnostic Algorithm and Nu-DESC in patients undergoing surgery under general anesthesia.
Detailed description
Accurate diagnosis for Greek speaking patients suffering from postoperative delirium is limited by the need for a translation of standardized tools that were investigated for their inter-rater reliability/agreement. Our primary aim is to validate the Greek version of the CAM Diagnostic Algorithm and Nu-DESC in patients undergoing surgery under general anesthesia. Our secondary aim is to estimate the diagnostic accuracy of NuDESK in our population. This study will provide the first official Greek translation of CAM and Nu-DESC, according to the ISPOR guidelines, and the first evaluation of their inter-rater agreement.
Interventions
OTHERCAM, Nu-DESC
Two trained raters, who are blinded and have no access to each other's evaluation, administer the CAM and Nu-DESC questionnaires in each shift, during the first postoperative day after the discharge from the post-anaesthesia care unit, independently. The two assessments are completed within 60 minutes of each other. If the research team set the diagnosis of POD, the appropriate treatment will be initiated, according to the Hospital's protocol
Sponsors
University of Thessaly
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. adult patients over 60 years of age 2. an American Society of Anesthesiologists (ASA) physical status I to III 3. undergoing elective non-cardiac surgery under general anaesthesia 4. native speakers of the Greek language 5. eligible to leave the post-anaesthesia care unit 6. an expected in-hospital stay of at least 24 hours following surgery
Exclusion criteria
1. refused to participate or sign the informed consent form 2. surgery or anaesthesia within the last 30 day 3. any prior or current history involving an affliction of the central nervous system 4. severe hearing or visual impairment 5. psychiatric disorders 6. sa core less than 5 according the Geriatric Depression Scale (GDS-15) 7. a score less than 4 for females and less than 2 for males according to the Lawton-Brody Instrumental Activities of Daily Living Scale (I.A.D.L.) 8. alcohol consumption less than 35 units/week 9. drug dependence 10. previous neuropsychological testing 11. haemodynamical instability 12. peri-procedural desaturation (one or more events of SpO2\<80% for more than 2 minutes)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Validation of the Greek version of the CAM Diagnostic Algorithm and Nu-DESC | 1st postoperative day | validate the Greek version of the CAM Diagnostic Algorithm and Nu-DESC |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Estimation of the inter-rater agreement of the Greek versions of the CAM and Nu-DESC | 1st postoperative day | estimate the inter-rater agreement of the Greek versions of the CAM and Nu-DESC |
| Incidence of POD in our study sample. | 1st postoperative day | Estimate the incidence of POD in our study sample. |
Countries
Greece
Outcome results
None listed