Ophthalmic Artery Resistance Index After Peribulbar Block in the Presence of Epinephrine

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04153123

Enrollment

Registered

2019-11-06

Start date

2013-12-01

Completion date

2014-05-31

Last updated

2019-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ophthalmic Artery, Peribulbar Block

Keywords

ocular flow, cataract surgery, peribulbar block, ocular Doppler

Brief summary

Evaluate ophthalmic artery flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine.

Detailed description

There are controversies regarding the ophthalmic artery (OA) flow after peribulbar block with the addition of epinephrine. Therefore, we aimed to evaluate OA flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine. Fifty-six patients that were eligible for cataract phacoemulsification surgery were selected. Patients were divided into two groups: group 1 - Peribulbar block with lidocaine and 1/200.000 epinephrine; group 2 - Peribulbar block with lidocaine in the absence of epinephrine. The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 min after the peribulbar block.

Interventions

DRUGEpinephrine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

The preparation of the syringes was performed by one of the researchers not involved in the execution of the blockades. The same anesthesiologist performed all the blocks, while the same ophthalmologist did the ocular monitoring measures.

Intervention model description

Group 1: Peribulbar anesthesia with 2% lidocaine with epinephrine 1/200,000. Group 2: Peribulbar anesthesia with 2% lidocaine without epinephrine.

Eligibility

Sex/Gender

ALL

Age

30 Years to 85 Years

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists (ASA) I, II or III physical status classification * Cataract surgery

Exclusion criteria

* glaucoma * diabetic retinopathy * previous eye surgery in the same eye * ocular trauma * allergic to any protocol medication * uncooperative patients or cognitive difficulties * axial eye diameter of less than 21.0 mm or greater than 25.5 mm.

Design outcomes

Primary

Measure	Time frame	Description
Artery resistance index of ophthalmic artery	Change on resistance index 10 minutes after peribulbar anesthesia	The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 minutes after the peribulbar block.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026