Desaturation
Conditions
Brief summary
To evaluate the effect of high flow nasal cannula for prevention of hypoxia during deep sedation in pediatric population
Interventions
DEVICEHigh flow nasal cannula
Oxygen is supplied via high flow nasal cannula. Heated air (2L/kg/min) is administered using Optiflow device (Fisher and Paykel Healthcare, Auckland, New Zealand).
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 6 Years
Healthy volunteers
No
Inclusion criteria
* Children aged \<7 years * ASA class I, II
Exclusion criteria
* Respiratory disease * Pneumothorax * Increased ICP * Nasal bleeding * Previous airway surgery * Trauma * Pulmonary hypertension
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of desaturation | During deep sedation (during approximately 1 hour after propofol infusion) | Incidence of peripheral pulse oximeter value lower than 95% |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of peripheral pulse oximeter value lower than 90% | During deep sedation (during approximately 1 hour after propofol infusion) |
| Incidence of changes in oxygen flow (control group) or FiO2 (HF group) | During deep sedation (during approximately 1 hour after propofol infusion) |
| Minimum pulse oximeter value | During deep sedation (during approximately 1 hour after propofol infusion) |
| Oxygen reserve index value | During deep sedation (during approximately 1 hour after propofol infusion) |
| Incidence of manual ventilation | During deep sedation (during approximately 1 hour after propofol infusion) |
| percutaneous CO2 value | During deep sedation (during approximately 1 hour after propofol infusion) |
Countries
South Korea
Contacts
Primary ContactJin-Tae Kim, MD, PhD
Outcome results
None listed