Metabolic Syndrome, Endovascular Aortic Repair
Conditions
Keywords
Metabolic Syndrome, EVAR
Brief summary
This prospective study aims to identify the prevalence of metabolic syndrome in patients undergoing EVAR and the implications of metabolic syndrome on the postoperative outcome, the major complications, the thromboembolic events and the perioperative mortality and morbidity of the patients undergoing vascular surgery.
Detailed description
Patients scheduled for elective EVAR will be randomly divided in two groups. One group patients with metabolic syndrome and one without. Metabolic syndrome is defined by the definition of 2009 as: Increased waist circumflex (\>94 cm in men and \> 80 cm in women), increased triglycerides or in therapy, decreased HDL (\< 40 mg/dl in men and \<50mg/dl in women) or in therapy, Increased blood pressure (Systolic Blood Pressure\>130 mmHg or Diastolic Blood Pressure\>85 mmHg) or in therapy, increased fasting glucose (\>100mg/dl) or in therapy. All the patients will be monitored throughout the perioperative period, at 30 days, 6 and 12 months, and any major or minor complication will be recorded.
Interventions
OTHEREVAR
Patients undergoing EVAR
Sponsors
University of Thessaly
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* elective EVAR
Exclusion criteria
* Patients incapable to give informed consent * Pregnancy * Cancer * Systematic Inflammatory disease * Use of steroids * Emergency surgery * Prior ICU admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | 30 days | Patients after EVAR who died in 30 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Systematic inflammatory response | 30 days | Patients after EVAR that develop Systematic inflammatory response |
| Postimplantation syndrome | 30 days | Patients after EVAR that develop Postimplantation syndrome |
| Renal insufficiency | 30 days | Patients after EVAR that develop Renal insufficiency |
| Thromboembolic events | 30 days | Incidence of thromboembolic events in patients after EVAR |
| Complications of surgical procedure | 30 days | Incidence of Complications of surgical procedure |
| Cardiovascular events | 30 days | Incidence of cardiovascular events in patients after EVAR |
Other
| Measure | Time frame | Description |
|---|---|---|
| Postoperative delirium (POD) | 30 days, 6 and 12 months | Prevalence of POD in patients undergoing EVAR |
Contacts
Primary ContactKonstantina Kolonia, MD
Backup ContactMetaxia Bareka, MD, PhD
Outcome results
None listed