Placenta Accreta
Conditions
Keywords
placenta accreta spectrum, MRI, score scale, diagnosis
Brief summary
Placenta Accreta Spectrum (PAS) is a disease associated with abnormal placental adhesion and invasion. In recent years, the incidence of PAS has increased significantly, which can cause massive postpartum hemorrhage, hysterectomy,and even maternal mortality. The research team of Peking university third hospital developed the ultrasound rating scale in china at first to conduct preliminary assessment of the PAS risk which can identify the severity of cases. In a basis of ultrasound, plan to explore the MRI for the the investigators diagnosis of PAS according to some specific PAS features, like the the uneven signal intensity , the myometrial discontinuity, and black band on T2 image, and finally established a MRI scoring system of PAS. MRI score system of PAS can reduce the subjective difference of the clinician's visual reading, and assist the clinician to assess the risk of sever PAS further, and conduct perioperative preparation to reduce the risk of maternal morbidity and mortality to achieve a better clinical outcome.
Detailed description
Placenta Accreta Spectrum (PAS) is a disease associated with abnormal placental adhesion and invasion. In recent years, the incidence of PAS has increased significantly, and the main risk is high hysterectomy rate,massive postpartum hemorrhage, and even maternal mortality in women at childbearing age. The research team of Peking university third hospital developed the ultrasound rating scale in china at first to conduct preliminary assessment of the PAS risk which can identify the severity of cases and guide the junior hospitals to transfer. Peking University third hospital is in the leading position in the preoperative diagnosis of PAS currently. Magnetic resonance imaging (MRI) has become a common method for preoperative evaluation for sever cases. MRI can provide a map of the placenta and PAS features, like the uterus enlarged significantly, the uneven signal intensity , the myometrial discontinuity, and black band on T2 image. It has a high diagnostic value. At present, only Lim and Ueno reported MRI scoring system for PAS. Due to the small sample size and the limitation of the research methods, a widely applicable rating scale has not been established. MRI score system of PAS can reduce the subjective difference of the clinician's visual reading, and assist the clinician to assess the risk of sever PAS further, and conduct perioperative preparation to reduce the risk of maternal morbidity and mortality and achieve a better clinical outcome.
Interventions
None listed
Sponsors
Peking University Third Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
1. Patients diagnosed as scarred uterus(with a history of cesarean section) 2. ultrasound score of PAS≥ 6 points who undergo MRI 3. Terminate pregnancy or childbirth in Peking university third hospital. -
Exclusion criteria
1. Patients who didn't undergo MRI 2. Patients who didn't deliver the baby in PUTH -
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of PAS diagnosed | one week after surgery | diagnose as PAS through clinical observation or specimen pathology after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood loss volume(ml) | 24 hours after surgery | The blood loss volume during the 24 hours after surgery |
| Rate of hysterectomy | two weeks after surgery | Number of patients who were performed hysterectomy/Number of patients with PAS |
| Rate of preterm labor | two weeks after surgery | The number of patients who delivered between 28 to 36+6 weeks/Number of patients with PAS |
| Blood transfusion volume(ml) | two weeks after surgery | the volume of blood transfusion |
Countries
China
Contacts
Primary ContactLian Chen
Outcome results
None listed