Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04147481

Enrollment

200

Registered

2019-11-01

Start date

2019-10-21

Completion date

2020-12-31

Last updated

2019-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Gastric Cancer, Rectal Cancer

Brief summary

To explore the effect of general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) on the recovery of patients with gastrointestinal tumor after surgical treatment.

Interventions

OTHERGroup Abdominal Nerve Block with local anesthetics

surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with 0.2% ropivacaine

OTHERGroup Abdominal Nerve Block with saline

surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with not 0.2% ropivacaine but 0.9% saline.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Aged 18 to 80 years. 2. ASA 1-3. 3. Clinical diagnosis of gastric carcinoma and colorectal cancer without metastasis. 4. Surgery for gastrointestinal surgery.

Exclusion criteria

1. Patients and their family members refuse to accept the clinical trial; 2. Complicated with acute cholangitis, gastrointestinal bleeding or ascites, etc.; 3. Hepatic encephalopathy, psychosis or neuropathy; 4. Body weight for acid-base and electrolyte imbalances, endotoxemia, and cachexia decreased by more than 2% or 5% in the past 2 months or 6 months. 5. Uncontrolled hypertentsion, coronary heart disease, diabetes.

Design outcomes

Primary

Measure	Time frame	Description
Incidence of postoperative chronic pain	6 month after operation	The incidence of chronic pain 6 month after operation

Secondary

Measure	Time frame	Description
Bedridden time	The postoperative duration up to 15 days	Postoperative bedridden time
Fasting time	The postoperative duration up to 15 days	Postoperative fasting time
Gastrointestinal decompression	The postoperative duration up to 15 days	Time of gastrointestinal decompression

Other

Measure	Time frame	Description
The numeric rating scale of postoperative pain	Within 7 days after surgery	The numerical rating scale (0-10) of posteoperaitve acute pain. If the NRS was larger than 4, we must take emergency action, including pressuring patient controlled analgesia pump, giving other analgesics.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026