Caries,Dental
Conditions
Brief summary
Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone. Materials and Methods: Patients (n=92, age 20-30y) with initial approximal enamel lesions on premolar and molar teeth (n=546) randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both remineralizing gel and ozone therapy. Caries lesions assessed on bitewing radiographs at baseline, after 1 year and after 2 years.
Interventions
OTHERApaCare & Repair
Initial cariuos lesions were treated.
Sponsors
Pomeranian Medical University Szczecin
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
-initial approximal enamel lesions on premolar and molar teeth
Exclusion criteria
* distal surface of the last tooth in arch, overlapping teeth * fillings on approximal surfaces of teeth of interest * ongoing orthodontic therapy with braces or other appliances
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Remineralizing effect | baseline | Caries lesions were assessed on bitewing radiographs |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Remineralizing effect - follow-up | after 1 year and after 2 years | Caries lesions were assessed on bitewing radiographs |
Outcome results
None listed