Chronic Obstructive Pulmonary Disease
Conditions
Keywords
activities of daily living, accessory inspiratory muscles, oxygen consumption, minute ventilation volume
Brief summary
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
Interventions
OTHERno intervention
no intervention in this study
Sponsors
National Cheng-Kung University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* 40 years or older * With the clinical diagnosis of COPD
Exclusion criteria
* With the clinical diagnosis of asthma or cancer * With cardiovascular, musculoskeletal and neurological diseases limiting physical activities in daily life * In the unstable medical state * MMSE under 25 * Barthel index score under 61
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiopulmonary exercise testing device | baseline | The machine analyze the breath of participants including oxygen consumption and minute ventilation volume. Oxygen consumption is reported in mL/min and minute ventilation volume is reported in L/min. |
| Surface electromyography device | baseline | The surface EMG is performed to assess the maximum voluntary contraction and muscle activity of upper limb muscles and accessory inspiratory muscles during performing simulated ADL tasks. The maximal voluntary contraction (MVC) is used as the reference level of muscle activity to normalize the EMG data of performing simulated ADL tasks. The muscle activity is reported in percentage. |
| The clinical Chronic Obstructive Pulmonary Disease questionnaire | baseline | This is a self-reported questionnaire to measure the impact of COPD on participants' health status. The rating scores is a 7-point scale (0=no limitation, 6=totally limited).Higher scores mean the more severe impact of COPD on participants' daily living. |
| Modified Borg Scale | baseline | This is a self-reported scale to measure how much participants perceive dyspnea. The range from 0 which means no difficulty to breathe to 10 which means with maximal difficulty to breathe. |
| Modified Medical Research Council | baseline | This is a five-point scale to assess the severity of breathlessness. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| EQ-5D questionnaire | baseline | This is a self-reported questionnaire for measuring generic health status |
Countries
Taiwan
Outcome results
None listed