Hematopoietic Stem Cell Transplantation, Nutrition
Conditions
Brief summary
The main objectives of this study were :(1) to comprehensively and systematically evaluate the nutritional status of patients after hematopoietic stem cell transplantation. (2) to explore the effect of nutritional factors on the prognosis of patients treated by hematopoietic stem cell transplantation.
Detailed description
This study is devised to investigate nutritional status in patients who have undergone hematopoietic stem cell transplantation in the First Affiliated Hospital of Soochow University. Evaluation time points include the day before receiving conditioning regimen, post-transplantation 180 days, the nutritional status of patients were systematically evaluated from the aspects of food intake, physical activity level, body composition, blood biochemistry, etc. Also, the effect of nutritional factors on prognosis of hematopoietic stem cell transplantaion patients will be evaluated.
Interventions
OTHERnot have
not have
Sponsors
The First Affiliated Hospital of Soochow University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients who undergo hematopoietic stem cell transplantation in the First Affiliated Hospital of Soochow University. * Having a life expectancy of more than 3 months
Exclusion criteria
* Not willing to participate in the investigation * Age less than 15 years old or more than 80 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline fat free mass at 6 months | 6 months | Body composition analyzer INBO DY S10 (bioelectrical impedance method) is used to analyze the content of fat free mass（ kilograms） |
| Change from Baseline fat mass at 6 months | 6 months | Body composition analyzer INBODY S10 (bioelectrical impedance method) is used to analyze the content of fat mass（ kilograms） |
| Change from Baseline food intake at 6 months | 6 months | 24-hour dietary record and semi-quantitative food frequency questionnaire are used to evaluate the eating condition of patients |
| Change from Baseline albumin level in blood at 6 months | 6 months | The content of albumin in blood is determined. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Overall survial | 3 years | It is measured from the date of entry into this trial to the date of death from any cause; patients not known to have died at last follow-up are censored on the date they were last known to be alive |
| Event free survival | 3 years | It is measured from the date of entry into this trial to the date of relapse from CR, or CRi, or death from any cause; patients not known to have any of these events are censored on the date they were last examined. |
Countries
China
Contacts
CONTACTSheng-Li Xue, M.D.
Outcome results
None listed