Triple Negative Breast Cancer
Conditions
Brief summary
The relationship between immune inflammation-related protein complexes in blood of triple negative breast cancer patients and recurrence or metastasis of breast cancer will be studied.
Detailed description
200 patients with triple negative breast cancer will be followed up. Peripheral venous blood was collected every 3 to 6 months. Change regularity of breast cancer-specific immune inflammation-related protein complexes in blood at different follow-up time points will be studied. The relationship between disease-specific protein complexes and pathological state of patients will be analyzed.
Interventions
None listed
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
36 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Female * Postoperative pathology confirmed invasive breast cancer after surgery for breast lump * Breast cancer-related chemotherapy and radiotherapy completed * triple negative breast cancer patients * age ≤ 60 years old
Exclusion criteria
* Male * Aged above 60 * Breast Carcinoma in situ * Women in pregnancy or breastfeeding * Suffering from other malignant tumors * Non-compliant patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| immune inflammation-related protein complexes | 2 years | The change of immune inflammation-related protein complexes which is measured by gel permeation chromatography. |
| blood markers | 2 years | The expression of CA153, CEA, CA125 in the blood of the patients, which are measured by electro-chemiluminescence immunoassay. |
Countries
China
Contacts
Primary ContactXi Shen
Outcome results
None listed