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Evaluation of the Muscular FORCE in the Upper Limbs of Patients Presenting a Thoracic Outlet Syndrome

Evaluation of the Muscular FORCE in the Upper Limbs of Patients Presenting a Thoracic Outlet Syndrome : Monocentric Case-control Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04145778
Acronym
EFORD
Enrollment
300
Registered
2019-10-31
Start date
2020-08-03
Completion date
2024-12-03
Last updated
2024-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Outlet Syndrome

Brief summary

The thoracic outlet syndrome is a rare but debilitating pathology, responsible for upper limb pain. Its frequency is probably underestimated because of diagnostic difficulties. This syndrome encompasses several entities including compressions of neurological, venous or arterial origin. In addition to pain, the majority of patients report fatigability and loss of strength in the upper limbs. However, the quantification of this loss of strength and fatigability has hardly been studied. In addition, the rehabilitation treatment is the first-line treatment of this pathology. It most often includes a muscle building phase. In this project, we would like to evaluate the proximal and distal force of patients presenting a thoracic outlet syndrome by comparing them to a population free from any pathology in the upper limbs. This evaluation would involve an isokinetic strength analysis of shoulder rotators at the proximal level, using an isokinetic dynamometer. At the distal level, the evaluation would be done using force clamps.Similarly, performing a 6-minute walk test will assess whether there is a difference between patients and controls, which may also impact endurance in addition to the pathology. In a second step, we will also be able to evaluate the effects of the reeducation on the strength and the muscular fatigability of the patients presenting a thoracic outlet syndrome.

Interventions

OTHER6-minute walk test

The 6-minute walk test is performed as part of routine practice for patients with BMDS to assess patients' overall endurance. In order to compare patients' global endurance with controls, this walking test will also be offered to 50 of the healthy subjects already recruited in the study.

Sponsors

Nantes University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
Yes

Inclusion criteria

* Age\> 18 years * Rehabilitative management of an thoracic outlet syndrome in the physical and rehabilitation department of Nantes University Hospital * Having given their consent by non-oral opposition. * Affiliated to a social security scheme

Exclusion criteria

* Mineurs * Majeurs under tutorship, curatorship or safeguard of justice * Pregnant or lactating women, protected persons * Patients with other pathology of the upper limb or shoulder (osteoarthritis, tendinopathies, amputation, ...). * Patients with non-stabilized pathologies, heart, respiratory, metabolic or neurological conditions * Associated pathology able to interfere with carrying out assessments

Design outcomes

Primary

MeasureTime frameDescription
Comparing proximal force between patients with thoracic outlet syndrome and healthy subjects1 yearIsokinetic evaluation of the internal shoulder rotators
Comparing distal force between patients with thoracic outlet syndrome and healthy subjects1 yearIsokinetic evaluation of the external shoulder rotators

Secondary

MeasureTime frameDescription
Evaluation of the effects in terms of strength of rehabilitation1 yearIsokinetic evaluation of rotators in strength
Evaluation of the effects in terms of fatigue of rehabilitation1 yearIsokinetic evaluation of rotators in fatigue
Evolution of cardiorespiratory performance1 monthEvalution of changes in cardiorespiratory performance using a 6-minute walk test.
Impact on pain1 yearVisual analogue pain scale (from 0 to 10: 0 absence of pain, 10 maximum pain imaginable)
Muscular fatigue in patients with thoracic outlet syndrome1 yearIsokinetic evaluation of internal and external shoulder rotator fatigue at 180 ° / s

Countries

France

Contacts

Primary ContactAlban FOUASSON-CHAILLOUX
Alban.FOUASSONCHAILLOUX@chu-nantes.fr+33-2 40 84 62 11

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026