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Nurse Led Ultrasound Guided Femoral Nerve Block in the Emergency Department

Acute Pain in Hip Fracture Patients: Pain Management in the Emergency Department, a Mixed Method Study¨. Nurse Led Ultrasound Guided Femoral Nerve Block in the Emergency Department

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04145752
Acronym
URGENT
Enrollment
42
Registered
2019-10-31
Start date
2020-02-11
Completion date
2022-12-31
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Femoral Neck Fractures, Hip Fractures

Keywords

femoral nerve block, Ultrasound guided, Nurse-led

Brief summary

The aim of this study is to investigate the effects of task shifting from anesthesiologists to special trained nurses performing femoral nerve block (FNB) in patients with hip fracture in the emergency department (ED) at Vestfold Hospital Trust (VHT). A sample of nurses (n= 6) will perform ultrasound guided FNB in hip fracture patients (n=25) admitted to the ED at VHT. This cohort will be compared to another cohort of hip fracture patients (n=25). This cohort will follow standard of care where the femoral nerve block is often performed by anesthesiologists. The study is a prospective, controlled randomized trial.

Detailed description

The ageing population admitted to the ED in developed countries is steadily increasing. Hip fractures are common among the elderly population, and related to increased mortality. Patient satisfaction with ED's has been an international challenge over several years. Acute pain is one of the most common reasons for patients coming admitted to the ED. However, undertreatment of pain is common, particularly in patients with hip fractures. Pain control can be difficult, and often requires intensive nursing and physician care, as elderly patients may manifest cardiovascular and respiratory complications from opioid administration. Optimizing acute pain management in patients with orthopedic trauma is important and can translate into significant positive physiologic and financial outcomes. At Vestfold Hospital Trust, pain relief of the hip fracture patient in ED has traditionally most often consisted of paracetamol and opiates. Additionally, the patients are offered FNB by the anesthesiologist, but concurrent conflicts and other organizational circumstances has have led to delayed block or no block for all or some patients. This often necessitate a continuation of pain relief in form of intravenous opioids, with increased risk of opioid side effects such as respiratory depression, delirium, constipation, urinary retention, nausea and vomiting and subsequently increased morbidity and increased costs for the hospital and the community. The investigators believe that shifting this task to nurses working in the ED can secure patient with hip fractures sufficiently and timely pain relief. By giving trained nurses this new task of performing FNB the investigators can study how expert nurses qualifications' are utilized to strengthen the quality of the ED. This study aims to implement and evaluate the introduction of specially trained nurses performing ultrasound guided FNB in patients with hip fractures in the ED. This implementation may be beneficial to patients in terms of prompt analgesia, reduced opioid consumption, thereby reducing opioid adverse events, and it might influence risk of complications and length of stay. The aim of this study is to evaluate cumulative Numeric Rating Scale (NRS) score during rest and during passive movement (30 degree flexion in the hip) in patients with hip fracture during stay in the ED at 120 minutes after admission, thereby comparing nurse-led FNB versus standard of care. The study has a randomized controlled trial design. Patients are randomized (1:1) into two groups: 1. Trained nurses in ED provide ultrasound guided single-shot FNB shortly after (at arrival ED) the patient is diagnosed with a hip fracture. 2. Nurses do not provide ultrasound guided single-shot FNB and the patient follows the FAST-TRACK-HIP FRACTURE course local guideline at our hospital. Hypothesis: A single shot FNB performed by nurses in the ED compared to todays practice will result in lower cumulative NRS score first 120 minutes after admission to ED than current practice.

Interventions

PROCEDURENurse-led femoral nerve block

The nurse perform a femoral nerve block in the emergency department in patients diagnosed with a hip fracture (x-ray)

Sponsors

University College of Southeast Norway
CollaboratorOTHER
Espen Lindholm
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

Prospective, randomized, controlled, open label trial

Eligibility

Sex/Gender
ALL
Age
18 Years to 110 Years
Healthy volunteers
No

Inclusion criteria

* Patients arriving at the emergency department diagnosed with a hip fracture (X-ray confirmed) * American Society of Anesthesiologists classification (ASA) 1-4 * Written informed consent by patient

Exclusion criteria

* Patients with dementia * Known allergies to local anesthetic used in femoral nerve block. * The patient is anticoagulated or uses platelet inhibitors. Acetylsalicylic acid and dipyridamole is allowed. If a recent (last 2 hours) International normalized ratio (INR) is below \<1.5 the patient can be included. * Pregnant * Age \<18 years * Severe head injury which leads to significant loss of consciousness (Glascow coma score (GCS) \<12) * \>10 mg or more morphine administrated pre-hospital * Skin lesions/infection at block site * Patients admitted with other suspected or verified fractures, except small fractures in hands and foots.

Design outcomes

Primary

MeasureTime frameDescription
Cumulative dynamic pain score - Numerical Rating Scale (NRS) - during passive movement at 120 minutes after start of procedure120 minutesCumulative dynamic pain score - Numerical Rating Scale (NRS) - during passive movement (30 degree flexion in the fractured hip) in patients with hip fracture during stay in the ED at 120 minutes after admission, measured by five time Points; At the end of procedure, 30 min.-, 60 min.-, 90 min.- and 120 min after start of procedure. NRS score: 0 is no pain and 10 is the worst pain.

Secondary

MeasureTime frameDescription
Number of total morphine equivalents - 24h24 hoursNumber of total morphine equivalents, mg (iv/po) administered during first 24 hours from admission at the emergency department
Number of total morphine equivalents - Hospital stayapprox. 6 daysNumber of total morphine equivalents, mg (iv/po) administered during total hospital stay.
Cumulative rest pain score -Numerical Rating Scale (NRS) - at 120 minutes after start of procedure120 minutesCumulative rest pain score NRS - Numerical Rating Scale (NRS) - in patients with hip fracture during stay in the emergency department at 120 minutes after admission, measured by five time Points; At the end of procedure, 30 min.-, 60 min.-, 90 min.- and 120 min after start of procedure. NRS score: 0 is no pain and 10 is the worst pain.

Other

MeasureTime frameDescription
Time from arrival at the emergency department to femoral nerve block is performedApprox 1 hourTime (min.) from arrival at emergency department (from Radiological Department) to femoral nerve block is performed.
Time from admission to surgery startsapprox. 48 hoursTime from admission to surgery starts, minutes
Length of total hospital stayApprox. 6 daysLength of total hospital stay, days
Mortality during hospitalizationApprox. 6 daysMortality during hospitalization, Yes or no
Mortality 30 days30 daysMortality at postoperative day 30, Yes or no
Hospital acquired pneumoniaApprox 6 daysHospital acquired pneumonia during hospital stay, Yes or no
Incidence of delirium during hospital stay.Approx. 6 daysIncidence of delirium, measured by Assessment test for delirium & cognitive impairment - 4AT, will be performed daily during hospital stay, number of patients
Acute renal failureApprox 6 daysAcute renal failure during hospital stay, Yes or no
Respiratory failureApprox 6 daysRespiratory failure during hospital stay, Yes or no
Intravasal injection24 hoursIntravasal injection - visually + circulatory and neurological symptoms, Yes or no
Hematoma24 hoursHematoma - defined as a new tumor \> 2 centimeter in the groin / injection site measured by ultrasound, Yes or no
Neurologic systemic outcomes / symptoms / paresthesiaApprox 6 daysNeurologic systemic outcomes / symptoms / paresthesia that have occurred after admission and which persist until discharge, numbers
Acute myocardial infarctionApprox 6 daysAcute myocardial infarction during hospital stay, Yes or no
RASS-score - Richmond Agitation and Sedation ScaleDaily - approx. 6 daysMeasure consciousness assessed by RASS-score - Richmond Agitation and Sedation Scale - (at admittance to the emergency department and daily). Total score. RAAS is a10-point scale, with four levels of anxiety or agitation (+1 to +4), one level to denote a calm and alert state (0), and 5 levels of sedation (-1 to -5) culminating in unarousable (-5).
Number of (mg) administered of antiemetics during hospital stayapprox. 6 daysNumber of (mg) administered of antiemetics ( ondansetron, dexagalen, metoclopramide) during first 24 hours and during hospital stay.
Time (minutes) to perform an ultrasound guided femoral nerve block performedapprox 30 minutesTime (minutes) used to perform an ultrasound guided femoral nerve block performed by nurses.

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026