Acute Kidney Injury
Conditions
Brief summary
In this exploratory study we explore the use of Shear Wave Elastography to differentiate between Acute Kidney Injury after vascular surgery and among the healthy population.
Interventions
DIAGNOSTIC_TESTShear Wave Elastography
Advanced ultrasound technique
Sponsors
University of Alabama at Birmingham
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* No history of diabetes or hypertension * Estimated Glomerular Filtration Rate \> 60 ml/min/m\^2 * Structurally normal kidney on renal ultrasound * BMI \< 27 kg/m\^2
Exclusion criteria
* Prisoners directly admitted from a correctional facility * Children \< 19 years or under 50 kg body weight if age is unknown * Patients with end stage renal disease or preexisting glomerular filtration rate less than or equal to 30 mL/min/1.73 m\^2 or need for dialysis * Patients with end stage heart disease on the cardiac transplant list * Patients undergoing procedures without vascular surgery * All transplant patients * Patients on ventricular assist devices * Patients undergoing emergency procedures * Patients with body mass index \> 27kg/m\^2 * Any condition that would impede visualization of the kidneys by ultrasound
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic factor of Shear Wave Elastography | From the time of Informed Consent being given to 96 hours after consent being given | Shear wave Elastography-derived Young's Elastic Modulus factor differentiating patients with Acute Kidney Injury post vascular surgery from healthy controls. |
Countries
United States
Contacts
Primary ContactAdam B Sturdivant, MPH
Backup ContactAyesha Bryant, MD, MSPH
Outcome results
None listed