Postoperative Pain
Conditions
Keywords
postoperative pain, pain sensitivity
Brief summary
This study aims to investigate the potential association between pain sensitivity questionnaire score, the severity of postoperative pain, and postoperative analgesic requirement in patients with open colorectal cancer surgery. This information may be used to guide the optimal postoperative pain management, and ultimately improve patient's quality of life.
Detailed description
We plan to investigate the predictive ability of the PSQ as well as experimental parameters of pain sensitivity using electronic algometer and other known risk factors for postoperative pain in 100 patients scheduled for open colorectal cancer surgery. The following items are investigated before surgery; Age, sex, level of education, type of surgery, past surgical history, presence of chronic pain, the expected maximal pain score (VAS) after surgery, Pain catastrophizing scale, anxiety scale (HADS-A), Pain sensitivity questionnaire, and pain threshold measured by electronic algometer. The total opioid consumption is investigated for 24 and 48 hours after surgery. In addition, the severity of postoperative pain is measured by the 11-point VAS at 24 and 48 hours after surgery. Patient satisfaction with postoperative pain control is also investigated at 48 hours after surgery using the 7-point patient's satisfaction scale.
Interventions
DEVICEElectronic digital pressure algometer
Evaluation of pain threshold using an algometer is conducted one day before surgery. The pressure of the plunger of algometer is applied vertically to the patient's right thenar muscle belly at a speed of 10 N/sec by the tester. Then the tester removes the algometer when the patients start to feel pain and record the pressure recorded on the algometer.
DIAGNOSTIC_TESTPain sensitivity questionnaire
Evaluation of pain threshold using the Korean-version pain sensitivity questionnaire is conducted one day before surgery.
Sponsors
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Intervention model description
Prospective observational study
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18 years or above * Patients scheduled for open colorectal cancer surgery under general anesthesia * ASA status I-III * Ability to read and understand the information sheet, questionnaires, and the - consent form * Patients scheduled for using IV-PCA after surgery
Exclusion criteria
* Unable to read and understand the information sheet, questionnaires, and the consent form * Severe medical or psychological diseases * Patients with preoperative chronic pain
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total fentanyl consumption during 24 hours | postoperative 24 hours | postoperative fentanyl consumption (mcg) via IV patient controlled analgesia |
| Total fentanyl consumption during 48 hours | postoperative 48 hours | postoperative fentanyl consumption (mcg) via IV patient controlled analgesia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain score | postoperative 24, 48 hours | 11-pointed NRS pain score at resting/coughing/movement NRS (0-10): 0, no pain; 10, worst pain imaginable |
| Patient satisfaction for postoperative pain management | postoperative 48 hours | 7-pointed likert scale (very satisfied-somewhat satisfied-satisfied-neutral-dissatisfied-somewhat dissatisfied-very dissatisfied) |
Contacts
Primary ContactJintae Kim, MD, PhD
Backup ContactHojin Lee, MD
Outcome results
None listed