Surgical Blood Loss, Third Molar
Conditions
Keywords
Warm Saline
Brief summary
The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.
Detailed description
The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively. For this purpose, 40 mandibular impacted third molars will be randomly allocated to two groups and surgically removed with the abovementioned saline temperatures. Finally, the suctioned liquids and duration of the surgeries will be carefully measured and compared between both sides.
Interventions
PROCEDUREwarm saline irrigation
The objective of this research was to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.
Sponsors
Tehran University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Being a candidate for bilateral mandibular third molar surgery * Both mandibular third molars must have a similar inclination to the second molar * Both mandibular third molars must have same Pell & Gregory's classification
Exclusion criteria
* Presence of any systemic condition or using any type of medication * History of allergy to local anesthetic (LA) solutions * Patients with an active gag reflex * Pregnant and post-menopause women * Patients with pericoronitis or any local inflammation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Amount of Bleeding in Cubic Centimetre | Intraoperatively, up to 30 minutes | both sides will be irrigated with 200cc of saline and the suctioned liquids will be carefully measured and compared |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Duration of the Surgery in Minutes | Intraoperatively, up to 30 minutes | both sides will be irrigated with 200cc of saline and the duration of the surgeries will be carefully measured and compared between both sides |
Countries
Iran
Participant flow
Pre-assignment details
In this study, the Enrollment number not equal to the number of participants who Started because this was a split-person design study in which 20 participants enrolled and within each individual, the left or right sides were allocated randomly for receiving these two types of saline.
Participants by arm
| Arm | Count |
|---|---|
| All Study Participants In this study, during impacted mandibular third molar surgery, one side was irrigated with room temperature saline of 25 ± 2 ° C as for the control side, while the other side was irrigated with normal saline of 37 ± 1 ° C as for the experimental side.
The side for each intervention was determined by a table of random numbers. | 20 |
| All Study Participants In this study, during impacted mandibular third molar surgery, one side was irrigated with room temperature saline of 25 ± 2 ° C as for the control side, while the other side was irrigated with normal saline of 37 ± 1 ° C as for the experimental side.
The side for each intervention was determined by a table of random numbers. | 40 |
| Total | 60 |
Baseline characteristics
| Characteristic | All Study Participants |
|---|---|
| Age, Continuous | 26.40 years STANDARD_DEVIATION 5.384 |
| Sex: Female, Male Female | 16 Participants |
| Sex: Female, Male Male | 4 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 0 |
| other Total, other adverse events | 0 / 20 |
| serious Total, serious adverse events | 0 / 0 |
Outcome results
Primary
Amount of Bleeding in Cubic Centimetre
both sides will be irrigated with 200cc of saline and the suctioned liquids will be carefully measured and compared
Time frame: Intraoperatively, up to 30 minutes
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Room Temperature Saline of 25 ± 2 ° C | Amount of Bleeding in Cubic Centimetre | 11.95 Cubic Centimeter | Standard Deviation 2.762 |
| Warm Saline of 37 ± 1 ° C | Amount of Bleeding in Cubic Centimetre | 8.75 Cubic Centimeter | Standard Deviation 2.593 |
Secondary
Duration of the Surgery in Minutes
both sides will be irrigated with 200cc of saline and the duration of the surgeries will be carefully measured and compared between both sides
Time frame: Intraoperatively, up to 30 minutes
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Room Temperature Saline of 25 ± 2 ° C | Duration of the Surgery in Minutes | 14.65 minutes | Standard Deviation 1.954 |
| Warm Saline of 37 ± 1 ° C | Duration of the Surgery in Minutes | 14.65 minutes | Standard Deviation 1.725 |