Predictors of Intracranial Hemorrhage in ARDS Patients on ECMO

Predictors of Intracranial Hemorrhage in Critically Ill Patients With Acute Lung Failure (ARDS) on Extracorporeal Membrane Oxygenation (ECMO)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04142775

Enrollment

1000

Registered

2019-10-29

Start date

2019-02-01

Completion date

2020-03-31

Last updated

2019-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS, Human, Extracorporeal Membrane Oxygenation Complication

Brief summary

Intracranial hemorrhage is is a rare, but critical incident in patients with acute lung failure undergoing ECMO therapy. Predictors of intracranial hemorrhage are yet to be defined to identify patients at (high) risk. This retrospective analysis investigates the predictive value and validity of parameters and specific risk factors of critically ill ARDS patients treated with ECMO.

Interventions

OTHERcomplication versus no complication

development of ICH

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ARDS following Berlin definition (mild, moderate, severe) * ECMO therapy (veno-venous cannulation)

Exclusion criteria

* ECMO, other than VV * ICH at initiation of ECMO * no cerebral CT scan at any time

Design outcomes

Primary

Measure	Time frame	Description
mortality	up to 28 days	mortality after ICH/no ICH in ARDS patients with ECMO

Secondary

Measure	Time frame	Description
ICU stay	up to 28 days	days on ICU
ventilator/ECMO-free days	up to 28 days	Ventilator/ECMO-free days

Countries

Germany

Contacts

Primary ContactMario Menk, PD Dr med

mario.menk@charite.de+4930450551002

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026