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Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity

Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04141332
Enrollment
160
Registered
2019-10-28
Start date
2018-02-01
Completion date
2019-03-01
Last updated
2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Specific Language Impairment

Brief summary

The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.

Detailed description

This study concentrates on the impact of epileptiform activity for childhood epilepsy on the speech and language disturbances in addition to the associated social, cognitive and intellectual dysfunctions.

Interventions

DIAGNOSTIC_TESTEEG was recorded by EEG Machines

EEG was recorded by EEG Machines

Sponsors

Mansoura University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Years to 6 Years
Healthy volunteers
Yes

Inclusion criteria

* 80 children were suffering from specific language impairment * 80 healthy children with age and sex match control group.

Exclusion criteria

* Previous history of perinatal hypoxic-ischemic damage * meningitis or encephalitis * motor weakness * hearing disorders * IQ below seventy * CP, social deprivation * autism and * psychiatric disorders .

Design outcomes

Primary

MeasureTime frameDescription
EEGs finding24-48 hoursEEGs finding were defined according to the followings Normal: within the range of frequency and amplitude distribution. Epileptiform: Describes transient background activity with a characteristic spikes, sharp waves, spike-slow wave or sharp-slow wave complexes of focal or generalized distribution. Abnormal non-epileptiform: deviations from normal in terms of background frequency patterns, usually in the form of excessive slow activity.

Other

MeasureTime frameDescription
Intelligence quotient (IQ)24-72 hoursAn intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence. Historically, IQ is a score obtained by dividing a person's mental age score, obtained by administering an intelligence test, by the person's chronological age, both expressed in terms of years and months. The resulting fraction is multiplied by 100 to obtain the IQ score. When current IQ tests were developed, the median raw score of the norming sample is defined as IQ 100 and scores each standard deviation (SD) up or down are defined as 15 IQ points greater or less.
social age24-48 hoursEvaluation of social age: using the Vineland Social Maturity Scale . VSMS was used along with a cognitive assessment to help make a diagnosis of mental retardation or intellectual disability. It has also been used extensively to assess the development of activities of everyday life.
cognitive age24-48 hoursEvaluation of cognitive age (mental age): using the Stanford Binet Intelligence Scale. The Stanford-Binet test is a examination meant to gauge intelligence through five factors of cognitive ability. These five factors include fluid reasoning, knowledge, quantitative reasoning, visual-spatial processing and working memory. Both verbal and nonverbal responses are measured.
language assessment24-72 hoursLanguage evaluation: by Comprehensive Arabic Language Test (CALT). The CALT was constructed by the members of the Department of Phoniatrics at Alexandria Main University Hospital, Egypt, to form a detailed comprehensive assessment battery for Arabic language and test its reliability and validity to use it in the early detection of subtle changes in the various components of language in cases of language impaired children.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026