Deep Sedation, Endotracheal Intubation
Conditions
Brief summary
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine. Inhaled sedation is possible with the Anesthetic-conserving device with a standard respirator. The pharmacodynamics and pharmacokinetics of halogenated agents allow deep sedation quickly after absorption. The feasibility of inhaled sedation has never been studied in hospital.
Detailed description
Retrospecive clinical monocentric study with sedated ventilated patients with isoflurane with the AnaConda® system out of hospital.
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patient sedated by isoflurane with Anesthetic-conserving device in pre-hospital * Major patient * not opposed to participating
Exclusion criteria
* Adults Under legal protection * patient refusal to participate in study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| depth of sedation | up to 1 day | depth of sedation (measured by the Ramsay Score) 10 minutes from start of the sedation and at stop of pre hospital sedation. The Ramsay score ranges level of sedation from 1(patient anxious ,agitated,restless) to 6 (patient exhibits no response). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| hemodynamic tolerance of patients during isoflurane sedation | up to 1 day | comparison of heart rate (heart beats per minute) before isoflurane start and 10 minutes from start of the sedation and at stop of pre hospital sedation |
Countries
France
Outcome results
None listed