Shrunken Pore Syndrome: a Retrospective, Single Center, Cohort Study

Kidney Diseases

CKD, Creatinine, Cystatin C, Cardiac surgery, GFR

To study the impact a difference in renal clearance of small and large molecules has on long-term survival.

Renal dysfunction is considered a major risk factor in cardiac surgery. Renal function has earlier been estimated by creatinine and more recently by cystatin C, both of which are analysed in a blood sample. New evidence seems to suggest that if the ratio between estimated renal function from cystatin C and creatinine is below 60% the patient has a higher rate of mortality irrespective of renal function. This syndrome is named Shrunken Pore Syndrome. We study patients whom have undergone elective cardiac surgery at our institution and on whom we before the surgery has collected blood samples. They are all included in our in house patient registry and qulaity database and afterwards we match this data to our national tax registry to get data on mortality. Our aim is to evaluate whether Shrunken Pore Syndrome influence mortality following elective cardiac surgery.

Sweden