Mastectomy, Subcutaneous, Sentinel Lymph Node Biopsy
Conditions
Brief summary
Sentinel Lymph Node Biopsy (SLNB) after nipple sparing mastectomy (NSM) is controversial. This study aims to investigate feasibility of SLNB with radioisotope method.
Detailed description
Volunteer patients who has underwent to NSM at least more than 6 months prior will be included to the study. Radioisotope will be injected via intradermal route to the breast underwent to NSM patients and lymphoscintigraphy images will be obtained to detect activity in axilla. If hot nodule is detected then it will be concluded that SLNB can be performed after NSM.
Interventions
DIAGNOSTIC_TESTSenti-Scint (99mTc- pertechnetate combined with human albumin)
Senti-Scint will be injected via intradermal route to the breast with history of previous NSM.
Sponsors
Acibadem University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
NSM with/without SLNB at least 6 months prior to this study -
Exclusion criteria
previous axillary dissection and active breast cancer \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Enhancement in axilla | 4 hours after injection | Hot nodules will be showed in axilla after injection of SENTI-SCINT |
Countries
Turkey (Türkiye)
Contacts
Primary ContactHalil KARA
Backup ContactAkif Enes Arikan
Outcome results
None listed