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Diagnostic Accuracy of the Vegetative and Minimally Conscious State

Diagnostic Accuracy of the Vegetative and Minimally Conscious State: Clinical Consensus Versus Standardized Neurobehavioral Assessment

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04139239
Enrollment
150
Registered
2019-10-25
Start date
2017-07-01
Completion date
2019-10-22
Last updated
2019-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorder of Consciousness, Minimally Conscious State

Keywords

Disorders of consciousness, Coma Recovery Scale-revision, Diagnostic accuracy

Brief summary

The aim of this study was to investigate diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment

Detailed description

In this study, DOC patients with clinical consensus of DOC were enrolled. The investigators used Coma Recovery Scale-revision (CRS-R) to assess consciousness levels for all DOC patients during ten days.

Interventions

DIAGNOSTIC_TESTComa Recovery Scale-revision

Patients were assessed by Coma Recovery Scale-revision to detect the DOC patients enrolled by clinicians.

Sponsors

Hangzhou Normal University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years

Inclusion criteria

Inclusion 1. at least 18 years old; 2. acquired brain injury; 3. no neuromuscular blockers or sedatives were used within 48 hours of enrollment.

Exclusion criteria

1. there are functional disorders caused by progressive mental diseases; 2. persistent seizures; 3. unstable vital signs; 4. double upper limb frustration, fracture.

Design outcomes

Primary

MeasureTime frameDescription
Assessed by the Coma Recovery Scale-RevisedWithin 10 daysAll patients were assessed by the Coma Recovery Scale-Revised within 10 days to detect the consciousness level. CRS-R consists of six sub-scales with 23 items, which evaluate the patients' auditory, visual, motor, Oromotor/Verbal, communication and arousal functions. For each subscale, the lower score reflected reflexivity related to the brain stem, while the higher score reflected non-reflexivity related to higher cortical functions (0-23).

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026