Analgesia, Anesthesia, Monitoring, Vascular Diseases, Cardiac Disease
Conditions
Brief summary
Comparison of twà different nociception monitors during general anesthesia
Detailed description
Analgesia remains a challenge in anesthesia. Several monitors have shown potential in detecting insufficient analgesia during general anesthesia, but they have not been investigated in patients undergoing cardiac and vascular surgery. In this study, we will compare skin conductance (Medstorm, Norway) and nol-index (Medasense, Israel) w during noxious and non-noxious stimuli. This study is carried out on patients included in another study (Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery).
Interventions
DEVICENol-Index
Multiparametric monitor that studies that establishes an index as a surrogate to nociception
DEVICESkin Conductance
Measures skin conductance as a surrogate to nociception
Sponsors
Erasme University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* moderate-to-high risk cardiac or vascular surgery * ASA 2-4
Exclusion criteria
* chronic arrhythmia (e.g. atrial fibrillation) * aortic insufficiency * pacemaker * implanted defibrillator * valve surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nol-Index response | 1 to 2 hours | Nol-Index (diminsenliss value from 0 to 100) will be assessed during noxious and non noxious stimuli |
| Skin conductance response | 1 to 2 hours | Peaks per second change during noxious and non noxious stimuli |
Countries
Belgium
Contacts
Primary ContactSean Coeckelenbergh, MD
Backup ContactLuc Barvais, MD, PhD
Outcome results
None listed