Diabetes
Conditions
Brief summary
This study investigates the effects of home-based resistance exercise training, compared to a control group, on body composition, muscle strength and glycaemic control in people with type 2 diabetes. Half participants will be in the home-based exercise group and half in the control group.
Interventions
BEHAVIORALHome-based
Resistance exercise carried out unsupervised at home
Sponsors
University of Glasgow
Dasman Diabetes Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Physician diagnosed type 2 diabetes * No changes in anti-diabetic medication in the last 3 months
Exclusion criteria
* Not currently or in the past year participating in any vigorous aerobic activity (\>1h per week) or any resistance exercise. * BMI of 45 or higher * Blood pressure of 160/100mmHg or higher * Currently receiving insulin therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycated Haemoglobin concentration (mmol/mol) | Change from baseline to 32 weeks | Glycated haemaglobin |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fat-free mass | Change from baseline to 32 weeks | Whole body fat free mass |
| Short performance physical battery test | Change from baseline to 32 weeks | Short performance physical battery test (0 (worst performance) to 12 (best performance)) |
Other
| Measure | Time frame | Description |
|---|---|---|
| BMI | Change from baseline to 32 weeks | Body mass index |
| Body fat | Change from baseline to 32 weeks | Total body fat measured via DEXA |
| Grip strength | Change from baseline to 32 weeks | Grip strength measured by handheld dynamometer |
| Physical activity levels | Change from baseline to 32 weeks | Physical activity levels measured with a wrist worn accelerometer |
| Quality of life score | Change from baseline to 32 weeks | EQ-5D-DL questionnaire will be used (5 (worst) to 125 (best)) |
| Visceral fat | Change from baseline to 32 weeks | Visceral adipose tissue measured by DEXA |
| One rep max | Change from baseline to 32 weeks | The maximum weight that can be lifted for a single repetition of leg extension and lateral pull down |
| Push up test | Change from baseline to 32 weeks | Number of push ups that can be performed |
Countries
Kuwait
Outcome results
None listed