Blood Pressure, Hypertension
Conditions
Brief summary
In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.
Interventions
None listed
Sponsors
Yan Li
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Male and female sex, aged 18-65 years 2. Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg 3. Hypertensive patients who are taking antihypertensive drugs 4. Willing to provide information about disease history and lifestyle 5. Willing to receive follow-up for up to 2-3 years 6. Sign the informed consent
Exclusion criteria
1. Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months 2. Having a history of atrial fibrillation or frequent arrhythmia 3. Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors 4. The subject is participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic classification in hypertension | 2 years | Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in different blood pressure measurement | 2 years | Differences in workplace blood pressure, daytime ambulatory blood pressure, home blood pressure and 24-hour ambulatory blood pressure |
| The distribution of heart rate in young and middle-aged subjects | 2 years | The distribution of heart rate in young and middle-aged subjects who were diagnosed with hypertension |
| Progression of target organ damage | 2 years | Differences in the progression of target organ damage between controlled or uncontrolled subjects or between subjects with fast and slow heart rate |
| The development of with-coat hypertension | 2 years | The development of white-coat hypertension as persistent hypertension and other types of hypertension or normal blood pressure and changes in target organ damage |
| The proportion of masked hypertension in patients with normal high blood pressure | 2 years | The proportion of masked hypertension in patients with normal high blood pressure and the change in outcome after treatment intervention and changes in target organ damage |
Countries
China
Outcome results
None listed