Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release

Use of Hyaluronic Acid Injection After Arthroscopic Lateral Release in Patellar Compression Syndrome With Degenerative Cartilage Changes: Randomized Control Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04134611

Enrollment

Registered

2019-10-22

Start date

2017-06-01

Completion date

2020-03-20

Last updated

2020-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Knee Pain Syndrome

Keywords

Hyaluronic acid injection, Knee Arthroscopy, lateral patellar retinaculae., lateral patellar compression syndrome

Brief summary

Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

Detailed description

This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

Interventions

DEVICEHyaluronic acid injection

Injection of Hyaluronic acid in knees of those who has degenerative changes after arthroscopic treatment of lateral patellar compression syndrome

DEVICENo injection of Hyaluronic acid

No injection of Hyaluronic acid was done

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

26 Years to 47 Years

Healthy volunteers

Inclusion criteria

* Lateral patellar compression syndrome

Exclusion criteria

* Patellar instability. * Smoking. * Diabetes Mellitus. * Previous knee surgery.

Design outcomes

Primary

Measure	Time frame	Description
Visual analogue score of knee pain	The VAS for knee pain was measured 24 months after operation	Visual analogue score of knee pain describe knee pain from degree 0 where no pain to degree 10 where is severe pain
Kujala score	Preoperative assessment and 2 year postoperatively	Kujala score questionnaire up to 100

Countries

Iraq

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026