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Effects of HIIT on Metabolic Syndrome

Study of the Effects of a Structured Training Program on People at Risk of Developing Metabolic Syndrome

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04133129
Enrollment
180
Registered
2019-10-21
Start date
2019-11-01
Completion date
2020-03-31
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Dyslipidemias, Metabolic Syndrome, Obesity, Sedentary Behavior

Keywords

HIIT, High Intensity Interval Training, Medium Intensity Continuous Training, Interval Training, Exercise, Physical Activity, Exercise Training

Brief summary

The project aims to find out the differences between two different types of structured training interventions have on the lipid profile of persons with diagnosed dyslipidemia. Each training intervention will last for 12 weeks. Subjects participating in the project will undergo a series of tests before and after the training intervention which will allow us to make conclusions.

Detailed description

The purpose of this project is to compare the effect that two different types of aerobic training modes have on the lipid profile of subjects with pre-symptoms of metabolic syndrome. One training mode will involve High-Intensity Interval Training and the other will involve medium intensity continuous training. The desired outcomes of this project are to know the effects of both modes of training have on the long-term on the lipid profile in order to help develop a nonpharmacologic alternative to prevent or treat metabolic syndrome and to know how affective and enjoyment responses are affected by the different modes of training. The Project lasts for 16 weeks. Training will take place during weeks 3 and 14 of the project. The project will be described fully to the participants during the 1st week. In addition to this, their rights as participants will be explained in addition to any possible ethical issues that might require clarifying. Once the subjects have agreed to take part in the research they will undergo a series of tests in order to asses their cardiorespiratory fitness and their lipids profile. Before starting the training intervention participants will be randomly assigned to one of the 3 different groups; Control, Medium Intensity Continuous Training and Low Volume High-Intensity Interval Training. Between weeks 3 and 14 subjects will take part in 3 training sessions per week. At week 15 and 16 subjects will undergo the same tests as during week 1 and 2.

Interventions

BEHAVIORALLow Volume-High Intensity Interval Training

On a treadmill, a 2 minute warm-up will be followed by 2 bouts of 4 minutes at an intensity between 85% and 95% of Maximum Heart Rate (HRmax) interspersed by a 2 minutes recovery bout at 70% of heart rate max, followed by a 3 minutes Cool Down

BEHAVIORALModerate Intensity Continuous Training

On a treadmill,a 2-minute warm-up will be followed by 45 minutes at 65%-75% of Heart Rate max followed by 3 minutes cool down.

Sponsors

INGESPORT HEALTH AND SPA CONSULTING SL
CollaboratorUNKNOWN
Coventry University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

Participants are only assigned to one of 3 possible groups for the duration of the intervention.

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Fasted Blood Glucose \>100 mg/dL * Total Cholesterol \>200 mg/dL * Blood Pressure \>130/90 mmHg * Do not partake in more than 150 min/week of moderate to vigorous exercise

Exclusion criteria

* Existing or past medical history of vascular disease, cancer, diabetes, osteoporosis, neurological, kidney, pulmonary, digestive (Coeliac disease), thyroidal disease. * Musculoskeletal injuries * Neuromuscular disorders or injuries * Individuals with a pacemaker

Design outcomes

Primary

MeasureTime frameDescription
Biochemical: Lipid Profile0 to 12 weeksEvaluate change in Very Low-Density Lipoproteins (VLDL), High Density Lipoprotein (HDL), and Low-Density Lipoprotein (LDL) in (mg/dl) with Liposcale® test, an advanced lipoprotein test based on 2D Nuclear Magnetic Resonance (NMR).
Blood Pressure (mmHg)0 to 12 weeksEvaluate change in Systolic and Diastolic Blood Pressure
Cardiorespiratory Fitness (ml/kg/min)0 to 12 weeksEvaluate change in maximal oxygen uptake (VO2max) via breath by breath analysis performed on a treadmill.
Changes in Body Composition (kg)0 to 12 weeksEvaluate changes in Fat-free mass, fat mass, skeletal muscle mass measured by bio-electrical impedance analysis.

Secondary

MeasureTime frameDescription
Changes in exercise enjoyment0 to 12 weeksThe investigators will assess perceived exercise enjoyment at baseline and post intervention using The Physical Activity Enjoyment Scale (PACES). (PACES) is an 18-item measure, scored on a 7-point bipolar scale based on the instruction; Please rate how you feel at the moment about the physical activity you have been doing:
Change in Behavioural Regulations in Exercise Questionnaire-2 (BREQ-2) over time0 to 12 weeksBehavioural Regulations in Exercise Questionnaire-2 (BREQ-2) is a 19 item self-report scale. It uses a Likert-type scale of 5 points, where 0 = not true for me and 4 = very true for me

Countries

Spain

Contacts

Primary ContactIsmael Serrablo, MSc
serrabli@uni.coventry.ac.uk0034652950339

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026