Acute Kidney Injury
Conditions
Brief summary
Total hip arthroplasty refers to the replacement of the femoral head and acetabulum damaged by disease or trauma with an artificial hip joint, thereby restoring joint activity and original function. Acute kidney injury is a common complication after total hip arthroplasty. Previous studies have shown that the incidence of acute kidney injury after hip replacement is as high as 21.9%. Acute kidney injury has become a global safety issue, and the occurrence of acute kidney injury can lead to an increase in hospital stay, medical costs and increased risk of death.There is currently no global survey of the incidence of AKI, and only a number of studies have been conducted on specific patient groups (eg, inpatients, intensive care units \[ICU\] patients or children) due to differences in study design and definition of acute kidney injury.
Detailed description
The incidence and prevalence of different studies vary widely, ranging from 0.32% to 44.30%. There are few studies on the risk factors associated with acute kidney injury after total hip arthroplasty, and early acute kidney injury is often overlooked due to the limitations of the current KDIGO-based diagnostic method. Therefore, it is particularly important for clinicians to understand the risk factors for postoperative acute kidney injury .
Interventions
None listed
Sponsors
Xuzhou Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients age 65 or older * One-sided joint replacement; * ASA score grade I-III
Exclusion criteria
* Emergency surgery patients; * Patients with severe liver and kidney dysfunction; * Missing related data; * Serious systemic diseases before surgery;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence and outcome of AKI after joint replacement | Within 7 days after surgery | AKI can be diagnosed if one of the following conditions is true: (1) Serum creatinine increases by ≥26.5 μmol/L (0.3 mg / dl) within 48 h; (2)Serum creatinine rises more than 1.5 times of the baseline value, and is significantly or presumably the above situation occurred within 7 days; |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Possible risk factors for AKI after joint replacement | 1 day before surgery | Patient's age, gender, height, weight |
| Intraoperative fluid volume and infusion type | during sugery and within 7days after surgery | Record the total amount of infusion and infusion type of during surgery |
| Hemodynamic changes | during sugery and within 7days after sugery | Focus on the fluctuation of mean arterial pressure |
| Factors related to anesthesia | during sugery and within 7days after sugery | Record the type and dose of anesthetic used in the procedure |
Countries
China
Contacts
Primary ContactJindong Liu, M.S
Outcome results
None listed