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Supervised Perturbation Training Results in Changes in Balance and Falling in Patients With Multiple Sclerosis

Supervised Perturbation Training Results in Changes in Balance and Falling in Patients With Multiple Sclerosis

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04132167
Enrollment
15
Registered
2019-10-18
Start date
2018-11-20
Completion date
2019-12-20
Last updated
2019-10-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis

Keywords

Rehabilitation, Multiple sclerosis, Tailored interventions

Brief summary

Physical exercise can prevent falls, certain types of exercise may be more effective. Perturbation-based balance training is a novel intervention involving repeated postural perturbations aiming to improve control of rapid balance reactions. The purpose of this study was to estimate the effect of perturbation- based balance training on falls and balance in daily life.Thirty patients with multiple sclerosis (PwMS) will assess with regard to dynamic balance, walking and falling. Patients randomly will allocate to a personalized (PRG) or traditional (TRG) rehabilitation group.

Detailed description

Thirty patients with multiple sclerosis (PwMS) will assess with regard to dynamic balance, walking and falling. Patients randomly will allocate to a personalized (PRG) or traditional (TRG) rehabilitation group.

Interventions

exercises for body stability in different positions (bridge, sitting, quadrupedal, half- kneeling, kneeling, standing, monopodalic) performed with visual biofeedback; transfers training performed in front of a mirror; ambulation training with courses drawn on the ground in a straight line and with more complex tracks with visual controlin particular using the protocols seated balance/strength training, standing bal- ance/weight-bearing training, mobility training and closed-chain training;

Sponsors

Suleyman Demirel University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* An age older than 18 years * Stable phase of the disease without relapses or worsening in the last three months * Referring fear of falling or a history of falls (at least one fall in the last year). * Individuals with a high level of balance.

Exclusion criteria

* Psychiatric disorders * Blurred vision * Severe cognitive impairment * Severely impaired upright postural control or limited participation in a rehabilitation program * Cardiovascular and respiratory disorders.

Design outcomes

Primary

MeasureTime frameDescription
dynamic balance6 weekthe effects of perturbation dynamic balance training assessed with four square step test \>15 seconds = increased risk of falls
walking6 weekthe effects of perturbation dynamic balance training assessed with 10 meter walking test
falling6 weekthe effects of perturbation dynamic balance training assessed with Falling Efficacy Scale(FES). The FES is a 10-item test. On a scale from 1 to 10, with 1 being very confident and 10 being not confident at all.
fear of falling6 weekThe short FES-I is a 7-item self-report questionnaire for measuring perceived self-efficacy to avoid a fall in various situations

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026