Glaucoma After Congenital And Infantile Cataract Surgery

Suspected Glaucoma and Glaucoma After Congenital and Infantile Cataract Surgery: A Longitudinal Study in China

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04131114

Enrollment

241

Registered

2019-10-18

Start date

2011-01-01

Completion date

2021-12-31

Last updated

2020-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Cataract, Glaucoma

Brief summary

Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and associated risk factors of suspected glaucoma/glaucoma for application in clinical standard care. Therefore, this study investigated the incidence of and risk factors for suspected glaucoma/glaucoma in patients who have undergone surgery for congenital/infantile cataracts.

Detailed description

A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2021 was performed.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 10 Years

Healthy volunteers

Inclusion criteria

* a diagnosis of congenital/infantile cataracts without any surgical intervention; * age younger than 10 years; * cataract surgery performed at the Zhongshan Ophthalmic Center after enrollment

Exclusion criteria

* a preoperative IOP above 21 mm Hg; * the presence of any preoperative sign of glaucoma, such as corneal enlargement, corneal clouding, excessive optic nerve cupping, or a family history of glaucoma; * the presence of ocular trauma or other abnormalities, such as microcornea, microphthalmia, persistent hyperplastic primary vitreous, Peters anomaly, congenital aniridia, Marfan syndrome, lens dislocation, retinitis pigmentosa, high myopia, fundus lesions, rubella, and Lowe syndrome.

Design outcomes

Primary

Measure	Time frame	Description
the incidence of suspected glaucoma/glaucoma after congenital cataracts	3 years	A Kaplan-Meier analysis was used.
Risk Factors of suspected glaucoma/glaucoma after congenital cataracts	3 years	Cox regression analysis was assessed

Countries

China

Contacts

Primary ContactHaotian Lin, Ph.D

gddlht@aliyun.com+86-020-87333271

Outcome results