Colorectal Neoplasms
Conditions
Brief summary
All adult patients with colorectal cancer presenting within the Sahlgrenska University Hospital or treated at any time at Sahlgrenska University Hospital are eligible and will be asked to participate. We already have biopsies taken at surgery in patients that receive surgery, but this study will include all patients and the biopsies will be taken during endoscopy for diagnosis of the primary tumour. Biopsies will then be taken during follow-up exams prior surgery but after neoadjuvant treatment. Biopsies will also be taken during surgery and in cases where surgery is not necessary biopsies will be taken regularly during follow-up exams. Blood samples and in relevant cases urinary samples and mouth swabs will be taken at all timepoints when biopsies are taken. If it is not possible to take biopsies prior treatment blood samples will still be drawn.
Interventions
No intervention, just observation of the differences between groups and within patients.
Sponsors
Göteborg University
Sahlgrenska University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Colorectal cancer
Exclusion criteria
* Not colorectal cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tumour response to treatment | 1-2 months after initiated treatment | Tumour microenviroment changes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Normal tissue response to treatment | 1month -3 years after treatment | Extra cellular matrix changes |
Countries
Sweden
Contacts
Primary ContactEva Angenete
Outcome results
None listed